HTR2A

Gene Symbol	HTR2A
Entrez Gene	3356
Alt Symbol	5-HT2A, HTR2
Species	Human
Gene Type	protein-coding
Description	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
Other Description	5-HT-2A|5-HT2 receptor|5-hydroxytryptamine receptor 2A|serotonin 5-HT-2A receptor
Swissprots	F5GWE8 B4DZ79 P28223 Q5T8C0 B2RAC5
Accessions	AAB22791 AAB24166 AAD14995 ACE96348 ACE96353 ACE96358 AGB76027 BAA90433 EAX08770 P28223 A23337 CAA01675 AA418604 AF498982 AAM21129 AK302787 BAG63991 AK314132 BAG36822 BC069356 AAH69356 BC069576 AAH69576 BC074848 AAH74848 BC074849 AAH74849 BC096839 AAH96839 BX647777 DA233936 DA247468 DC321645 DN990785 M86841 AAA58354 S71229 AAB31320 X57830 CAA40963 NM_000621 NP_000612 NM_001165947 NP_001159419
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle con
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell projection, dendrite {ECO:0000250}. Cell projection, axon {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Membrane, caveola {ECO:0000250}. Note=Localizes to the postsynaptic thickening of axo-dendritic synapses. {ECO:0000250}.
Tissue Specificity	Detected in brain cortex (at protein level). Detected in blood platelets. {ECO:0000269|PubMed:18297054}.
Top Pathways	Gap junction, Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HTR2A / 5-HT2A Receptor ELISA Kit (Sandwich ELISA) - LS-F8839 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156-10 ng/ml

Human HTR2A ELISA Kit - abx151879 from Abbexa Category ELISA Kit Sensitivity 0.057 ng/ml Range 0.156 ng/ml - 10 ng/ml

5-hydroxytryptamine receptor 2A (HTR2A), Human, ELISA Kit - CSB-EL010887HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

5-Hydroxytryptamine Receptor 2A (HTR2A), Human, ELISA Kit - SED486Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.057ng/mL Range 0.156-10ng/mL

5-hydroxytryptamine receptor 2A (HTR2A), Human, ELISA Kit - E01H1397 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

5-hydroxytryptamine (serotonin) receptor 2A, ELISA Kit - MBS908820 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5 hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7215991 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2A, ELISA Kit - MBS077608 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2A, ELISA Kit - MBS076602 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2A, ELISA Kit - MBS058692 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2A, ELISA Kit - MBS077673 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2A, ELISA Kit - MBS094393 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2A, ELISA Kit - MBS070088 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2A, ELISA Kit - MBS079836 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7201587 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7228735 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7223113 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7205962 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7243861 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-Hydroxytryptamine Receptor 2A (HTR2A), ELISA Kit - MBS2020958 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.057ng/mL. Range 0.156-10ng/mL

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7208286 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7213677 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7214716 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7229609 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

5-hydroxytryptamine receptor 2A (HTR2A), ELISA Kit - MBS7226071 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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