UBE2T

Gene Symbol	UBE2T
Entrez Gene	29089
Alt Symbol	HSPC150, PIG50
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2T
Other Description	HSPC150 protein similar to ubiquitin-conjugating enzyme|cell proliferation-inducing gene 50 protein|ubiquitin carrier protein T|ubiquitin conjugating enzyme|ubiquitin-conjugating enzyme E2 T|ubiquitin-conjugating enzyme E2T (putative)|ubiquitin-protein ligase T
Swissprots	Q2TU36 Q9NPD8
Accessions	CAI84529 EAW91411 EAW91412 EAW91413 EAW91414 EAW91415 Q9NPD8 AB032931 BAA93711 AF160215 AAF67016 AF161499 AAF29114 AK000504 BAA91211 AY542309 AAT08178 BC004152 AAH04152 BC019284 AAH19284 BG776416 DQ892729 ABM83655 DQ895975 ABM86901 NM_014176 NP_054895
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination. {ECO:0000269|PubMed:16916645, ECO:0000269|PubMed:17938197, ECO:0000269|PubMed:19111657, ECO:0000269|PubMed:19589784, ECO:0000269|PubMed:19887602, ECO:0000269|PubMed:20061386}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:17938197, ECO:0000269|PubMed:19887602}. Note=Accumulates to chromatin.
Top Pathways	Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Canine E2 ELISA kit - 55R-2105 from Fitzgerald Category ELISA Kit Prices $525.00 Sizes 96 tests

Chicken E2 ELISA kit - 55R-2103 from Fitzgerald Category ELISA Kit Prices $525.00 Sizes 96 tests

Human E2 ELISA kit - 55R-2107 from Fitzgerald Category ELISA Kit Prices $525.00 Sizes 96 tests

Mouse E2 ELISA kit - 55R-2111 from Fitzgerald Category ELISA Kit Prices $525.00 Sizes 96 tests

Porcine E2 ELISA kit - 55R-2113 from Fitzgerald Category ELISA Kit Prices $525.00 Sizes 96 tests

Rabbit E2 ELISA kit - 55R-2109 from Fitzgerald Category ELISA Kit Prices $525.00 Sizes 96 tests

UBE2T (Human) IP-WB Antibody Pair - H00029089-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

UBE2T (Human) IP-WB Antibody Pair - H00029089-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

UBE2T (Human) IP-WB Antibody Pair - H00029089-PW3 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

ubiquitin-conjugating enzyme E2T (putative) , ELISA Kit - MBS9338696 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml Range 0.625 ng/ml - 20 ng/ml

Human UBE2T / HSPC150 ELISA Kit (Competitive EIA) - LS-F27687 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 1 ng/ml Range 1-25 ng/ml

Mouse UBE2T / HSPC150 ELISA Kit (Competitive EIA) - LS-F28322 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 0.1 ng/ml Range 1-25 ng/ml

Human UBE2T ELISA Kit - E101880 from Biobool Category ELISA Kit

anti-HSPC150 / UBE2T antibody - ARG63296 from Arigo Biolaboratories Category ELISA Kit

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