IFNAR2

Gene Symbol IFNAR2
Entrez Gene 3455
Alt Symbol IFN-R, IFN-alpha-REC, IFNABR, IFNARB
Species Human
Gene Type protein-coding
Description interferon (alpha, beta and omega) receptor 2
Other Description IFN-R-2|IFN-alpha/beta receptor 2|human interferon alpha/beta receptor|interferon alpha binding protein|interferon alpha/beta receptor 2|interferon-alpha/beta receptor beta chain|type I interferon receptor 2
Swissprots A8KAJ4 Q6FHD7 Q15467 P48551 D3DSE9 D3DSE8
Accessions AAB46417 AAB46418 AAB46419 AAU21038 EAX09842 EAX09843 EAX09844 EAX09845 EAX09846 P48551 AK293059 BAF85748 BC002793 AAH02793 BC013156 BG715143 BI520056 BM677386 CD110317 CR541817 CAG46616 DQ893015 ABM83941 DQ896260 ABM87259 HG380509 CDG37809 HY104613 L41942 AAB46413 L41943 AAB46414 L41944 AAB46415 U29584 AAC50202 X77722 CAA54785 X89772 CAA61914 X89814 CAA61940 NM_000874 NP_000865 NM_001289125 NP_001276054 NM_001289126 NP_001276055 NM_001289128 NP_001276057 NM_207584 NP_997467 NM_207585 NP_997468
Function Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity. {ECO:0000269|PubMed:11682488, ECO:0000269|PubMed:12105218, ECO:0000269|PubMed:7665574, ECO:0000269|PubMed:7759950, ECO:0000269|PubMed:8181059}.
Subcellular Location Isoform 3: Secreted.
Tissue Specificity Isoform 3 is detected in the urine (at protein level). Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines. {ECO:0000269|PubMed:7588638, ECO:0000269|PubMed:7759950, ECO:0000269|PubMed:8181059}.
Top Pathways Osteoclast differentiation, PI3K-Akt signaling pathway, Herpes simplex infection, Influenza A, Measles

IFNAR2-Over-expression-Lysate - LY12743a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag IFNAR2 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 2) or transiently transfected with theIFNAR2 gene

IFNAR2 293T Cell Transient Overexpression Lysate(Denatured) - H00003455-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

IFNAR2 overexpression lysate - LY403927 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

IFNAR2 overexpression lysate - LY430997 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

IFN-alpha/beta R2 Overexpression Lysate (Denatured) - H00003455-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: IFNAR2 transfected lysate (37.4 KDa). Lane 2: Non-transfected lysate.

IFN-α/βRβ (h2): 293T Lysate - sc-159501 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

Human IFNAR2 / IFNABR HEK293 Cell Lysate (WB positive control) - 10359-H08HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human IFNAR2 / IFNABR HEK293 Cell Lysate (WB positive control) - 10359-H02HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human IFNAR2 Human Cells Transfected Lysate (positive control) (denatured) - orb173509 from Biorbyt

Category Cell Lysate
Prices $425.00
Sizes 300 μg
Species Human

IFN-alpha/beta R2 Overexpression Lysate (Native) - NBP2-04481 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: IFNAR2 Overexpression Lysate (Adult Normal) [NBP2-04481] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IFNAR2.

IFN-alpha/beta R2 Overexpression Lysate (Native) - NBP2-10131 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: IFNAR2 Overexpression Lysate (Adult Normal) [NBP2-10131] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IFNAR2.

IFN-alpha/beta R2 Overexpression Lysate (Denatured) - H00003455-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Human IFNAR2 Human Cells Transfected Lysate (positive control) (denatured) - orb173508 from Biorbyt

Category Cell Lysate
Prices $604.00
Sizes 300 μg
Species Human

Panoply™ Human IFNAR2 Knockdown Stable Cell Line - CSC-DC007450 from Creative biogene

Category Cell Line
Species Human

IFNAR2 Knockout Cell Line-HeLa - CSC-RT2071 from Creative biogene

Category Cell Line
Species Human

IFNAR2 KO Cell Lysate-HeLa - CLKO-1932 from Creative biogene

Category Cell Lysate
Search more