IFNAR2

Gene Symbol	IFNAR2
Entrez Gene	3455
Alt Symbol	IFN-R, IFN-alpha-REC, IFNABR, IFNARB
Species	Human
Gene Type	protein-coding
Description	interferon (alpha, beta and omega) receptor 2
Other Description	IFN-R-2|IFN-alpha/beta receptor 2|human interferon alpha/beta receptor|interferon alpha binding protein|interferon alpha/beta receptor 2|interferon-alpha/beta receptor beta chain|type I interferon receptor 2
Swissprots	A8KAJ4 Q6FHD7 Q15467 P48551 D3DSE9 D3DSE8
Accessions	AAB46417 AAB46418 AAB46419 AAU21038 EAX09842 EAX09843 EAX09844 EAX09845 EAX09846 P48551 AK293059 BAF85748 BC002793 AAH02793 BC013156 BG715143 BI520056 BM677386 CD110317 CR541817 CAG46616 DQ893015 ABM83941 DQ896260 ABM87259 HG380509 CDG37809 HY104613 L41942 AAB46413 L41943 AAB46414 L41944 AAB46415 U29584 AAC50202 X77722 CAA54785 X89772 CAA61914 X89814 CAA61940 NM_000874 NP_000865 NM_001289125 NP_001276054 NM_001289126 NP_001276055 NM_001289128 NP_001276057 NM_207584 NP_997467 NM_207585 NP_997468
Function	Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity. {ECO:0000269|PubMed:11682488, ECO:0000269|PubMed:12105218, ECO:0000269|PubMed:7665574, ECO:0000269|PubMed:7759950, ECO:0000269|PubMed:8181059}.
Subcellular Location	Isoform 3: Secreted.
Tissue Specificity	Isoform 3 is detected in the urine (at protein level). Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines. {ECO:0000269|PubMed:7588638, ECO:0000269|PubMed:7759950, ECO:0000269|PubMed:8181059}.
Top Pathways	Osteoclast differentiation, PI3K-Akt signaling pathway, Herpes simplex infection, Influenza A, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IFNAR2 protein (Fc Chimera) - ab83680 from Abcam Category Protein Prices $282.00 Sizes 25 µg Source HEK 293 cells Species Human

Human IFNAR2 protein fragment - ab151876 from Abcam Category Protein Source HEK 293 cells Species Human

Human IFNAR2 protein fragment - ab185868 from Abcam Category Protein Source Mammalian Species Human

IFNAR2 Antibody Blocking Peptide - LS-E26625 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IFN-alpha/beta R2 Partial Recombinant Protein - H00003455-Q01 from Novus Biologicals Category Protein Prices $319.00 Sizes 25 ug 10 ug Species Human

Recombinant Human IFN-alpha/beta R2 Fc Chimera, CF - 4015-AB-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant human Interferon alpha/beta receptor 2 (OPCA00917) - OPCA00917 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human IFNAR2 Fc tag protein - orb83890 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human IFNAR2 protein - orb246364 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human IFNAR2 protein - orb180300 from Biorbyt Category Protein Prices $306.00, $400.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source Human Cells Species Human

Human IFNAR2 protein - orb245504 from Biorbyt Category Protein Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human IFNAR2 His tag protein - orb83891 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human IFNAR2 protein - orb49453 from Biorbyt Category Protein Prices $272.00, $366.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Goat anti IFNAR2 antibody Immunizing peptide - orb17071 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

IFNAR2 Peptide - AC21-1461-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

IFNAR2 - H00003455-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

IFNAR2 - H00003455-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Interferon alpha, beta Receptor 2, IFNAR2, Human, Recombinant - 19-C476 from ARP American Research Products Category Protein Prices $109.00 Sizes 10 µg Source HEK293 Species Human

IFNAR2 Peptide - 46-858P from ProSci Category Peptide

IFNAR 2 Recombinant Protein - 96-407 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

IFNAR 2 Recombinant Protein - 96-408 from ProSci Category Protein Prices $2,025.00 Sizes 1 mg Source HEK293 cells Species Human

IFNAR2 fusion protein - ag0191 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli-derived, PGEX-4T Species Human

IFNAR2 fusion protein - Ag16951 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Interferon-Omega 1 Protein - BP002448-CYT-040 from Syd Labs Category Protein Prices $160.00, $990.00 Sizes 100 µg, 1 mg Source E. coli-derived. Species Human

Recombinant Human IFNAR2, Fc Chimera - IFNAR2-25H from Creative Biomart Category Protein Source Human 293 cells .

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