IFNAR2

Gene Symbol	IFNAR2
Entrez Gene	3455
Alt Symbol	IFN-R, IFN-alpha-REC, IFNABR, IFNARB
Species	Human
Gene Type	protein-coding
Description	interferon (alpha, beta and omega) receptor 2
Other Description	IFN-R-2|IFN-alpha/beta receptor 2|human interferon alpha/beta receptor|interferon alpha binding protein|interferon alpha/beta receptor 2|interferon-alpha/beta receptor beta chain|type I interferon receptor 2
Swissprots	A8KAJ4 Q6FHD7 Q15467 P48551 D3DSE9 D3DSE8
Accessions	AAB46417 AAB46418 AAB46419 AAU21038 EAX09842 EAX09843 EAX09844 EAX09845 EAX09846 P48551 AK293059 BAF85748 BC002793 AAH02793 BC013156 BG715143 BI520056 BM677386 CD110317 CR541817 CAG46616 DQ893015 ABM83941 DQ896260 ABM87259 HG380509 CDG37809 HY104613 L41942 AAB46413 L41943 AAB46414 L41944 AAB46415 U29584 AAC50202 X77722 CAA54785 X89772 CAA61914 X89814 CAA61940 NM_000874 NP_000865 NM_001289125 NP_001276054 NM_001289126 NP_001276055 NM_001289128 NP_001276057 NM_207584 NP_997467 NM_207585 NP_997468
Function	Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity. {ECO:0000269|PubMed:11682488, ECO:0000269|PubMed:12105218, ECO:0000269|PubMed:7665574, ECO:0000269|PubMed:7759950, ECO:0000269|PubMed:8181059}.
Subcellular Location	Isoform 3: Secreted.
Tissue Specificity	Isoform 3 is detected in the urine (at protein level). Expressed in blood cells. Expressed in lymphoblastoid and fibrosarcoma cell lines. {ECO:0000269|PubMed:7588638, ECO:0000269|PubMed:7759950, ECO:0000269|PubMed:8181059}.
Top Pathways	Osteoclast differentiation, PI3K-Akt signaling pathway, Herpes simplex infection, Influenza A, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-IFNAR2-cDNA-Clone - DC01113 from Abgent, a WuXi AppTec company Prices $446.85 Sizes 10 µg Species Human Accession BC002793

IFNAR2 - MBS1278554 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC002793

Human IFNAR2 cDNA clone(NM_207585.1) - CDFG013887 from Creative Biomart Species Human Accession NM_207585.1

Human IFNAR2 cDNA clone(NM_207584.1) - CDFG013888 from Creative Biomart Species Human Accession NM_207584.1

Human IFNAR2 cDNA clone(NM_000874.3) - CDFH009013 from Creative Biomart Species Human Accession NM_000874.3

Human IFNAR2 ORF Clone(NM_207584.1) - CDCR328227 from Creative Biomart Species Human Accession NM_207584.1

Human IFNAR2 ORF Clone(NM_207584.1) - CDCR328228 from Creative Biomart Species Human Accession NM_207584.1

Human IFNAR2 ORF Clone(NM_207585.1) - CDCR328229 from Creative Biomart Species Human Accession NM_207585.1

Human IFNAR2 ORF Clone(NM_207585.1) - CDCR328230 from Creative Biomart Species Human Accession NM_207585.1

Human IFNAR2 ORF Clone(NM_000874.3) - CDCR337900 from Creative Biomart Species Human Accession NM_000874.3

Human IFNAR2 ORF Clone(NM_000874.3) - CDCR337901 from Creative Biomart Species Human Accession NM_000874.3

Human IFNAR2 ORF Clone(NM_000874.3) - CDCL166856 from Creative Biomart Species Human Accession NM_000874.3

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone in cloning vector - HG10359-M from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10359-UT from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10359-NF from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10359-CY from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10359-NM from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10359-CF from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10359-NY from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10359-CH from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10359-CM from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10359-ACR from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10359-ACG from Sino Biological Species Human

Human IFNAR2/IFNABR transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10359-NH from Sino Biological Species Human

Human IFN-alpha/beta R2 (NP_997468) VersaClone cDNA - RDC1361 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

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