IREB2

Gene Symbol	IREB2
Entrez Gene	3658
Alt Symbol	ACO3, IRP2, IRP2AD
Species	Human
Gene Type	protein-coding
Description	iron-responsive element binding protein 2
Other Description	IRE-BP 2|iron regulatory protein 2|iron-responsive element-binding protein 2
Swissprots	Q9UF17 Q8WVK6 H0YKU0 P48200 Q13095 Q1HE21 A8KAC7 E1CJT9 Q59FQ7
Accessions	ABF47091 EAW99169 EAW99170 EAW99171 P48200 AB209403 BAD92640 AB586699 BAJ19024 AK027033 AK027034 AK292992 BAF85681 AL117613 AL133439 CAB62825 BC017880 AAH17880 BC117481 AAI17482 BC117483 AAI17484 BC143948 BX340905 CN290278 HQ258663 ADR83414 M58511 AAA69901 U20180 AAA79926 NM_004136 NP_004127
Function	RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'- UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. {ECO:0000269|PubMed:7983023}.
Subcellular Location	Cytoplasm.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IREB2 293T Cell Transient Overexpression Lysate(Denatured) - H00003658-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

IREB2 293T Cell Transient Overexpression Lysate(Denatured) - H00003658-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

IREB2 293 Cell Lysate - 408489 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

IRP2 Overexpression Lysate (Denatured) - H00003658-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

IRP2 Overexpression Lysate (Native) - NBL1-12029 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

IREB2 Over-expression Lysate Product - GWB-7BAD9C from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

IRP2 Overexpression Lysate (Denatured) - H00003658-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human IREB2 Knockdown Stable Cell Line - CSC-DC007734 from Creative biogene Category Cell Line Species Human

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