IREB2

Gene Symbol IREB2
Entrez Gene 3658
Alt Symbol ACO3, IRP2, IRP2AD
Species Human
Gene Type protein-coding
Description iron-responsive element binding protein 2
Other Description IRE-BP 2|iron regulatory protein 2|iron-responsive element-binding protein 2
Swissprots Q9UF17 Q8WVK6 H0YKU0 P48200 Q13095 Q1HE21 A8KAC7 E1CJT9 Q59FQ7
Accessions ABF47091 EAW99169 EAW99170 EAW99171 P48200 AB209403 BAD92640 AB586699 BAJ19024 AK027033 AK027034 AK292992 BAF85681 AL117613 AL133439 CAB62825 BC017880 AAH17880 BC117481 AAI17482 BC117483 AAI17484 BC143948 BX340905 CN290278 HQ258663 ADR83414 M58511 AAA69901 U20180 AAA79926 NM_004136 NP_004127
Function RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'- UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. {ECO:0000269|PubMed:7983023}.
Subcellular Location Cytoplasm.

IRP-2 CRISPR/Cas9 KO Plasmid (h) - sc-401710 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRP-2 HDR Plasmid (h) - sc-401710-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRP-2 Double Nickase Plasmid (h) - sc-401710-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRP-2 Double Nickase Plasmid (h2) - sc-401710-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRP-2 CRISPR Activation Plasmid (h) - sc-401710-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRP-2 CRISPR Activation Plasmid (h2) - sc-401710-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRP-2 Lentiviral Activation Particles (h) - sc-401710-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRP-2 Lentiviral Activation Particles (h2) - sc-401710-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IRP-2 siRNA (h) - sc-40715 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRP-2 shRNA Plasmid (h) - sc-40715-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRP-2 shRNA (h) Lentiviral Particles - sc-40715-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IRP2 RNAi - H00003658-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU042681 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10761 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10761 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

IREB2 siRNA (Human) - CRH2451 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IREB2 - MBS8230707 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IREB2 (NM_004136.2) - SHH320545 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human IREB2(NM_004136.2) - SHL173496 from Creative biogene

Category siRNA
Species Reactivities Human

IREB2 shRNA Plasmid (Human) - CHH2451 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IREB2 miRNA 3'UTR clone - MiUTR1H-04989 from Creative biogene

Species Reactivities Human
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