ACTL6A

Gene Symbol ACTL6A
Entrez Gene 86
Alt Symbol ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K
Species Human
Gene Type protein-coding
Description actin-like 6A
Other Description 53 kDa BRG1-associated factor A|BAF complex 53 kDa subunit|BAF53|BRG1-associated factor 53A|INO80 complex subunit K|actin-like protein 6A|actin-related protein 4|actin-related protein Baf53a|arpNbeta|hArpN beta
Swissprots O96019 B3KMN1 Q8TAE5 Q9BVS8 Q9H0W6 D3DNR9
Accessions EAW78397 EAW78398 EAW78399 EAW78400 EAW78401 O96019 AA256726 AB015907 BAA74577 AB060168 BAB87844 AB061315 BAB87848 AF041474 AAC94991 AK021756 BAG51043 AK098691 AK223212 BAD96932 AL136608 CAB66543 BC000949 AAH00949 BC001391 AAH01391 BC035463 BC036371 AAH36371 CR533529 CAG38560 DB041143 EU832285 ACE87542 EU832370 ACE86855 HQ448270 ADQ32750 NM_004301 NP_004292 NM_177989 NP_817126 NM_178042 NP_829888
Function Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for maximal ATPase activity of SMARCA4/BRG1/BAF190A and for association of the SMARCA4/BRG1/BAF190A containing remodeling complex BAF with chromatin/nuclear matrix. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF
Subcellular Location Nucleus {ECO:0000269|PubMed:18026119}.

BAF53 (C-7) - sc-271011 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAF53 (C-7): sc-271011. Western blot analysis of BAF53 expression in HeLa (A), K-562 (B) and Ramos (C) whole cell lysates.

BAF53 (D-3) - sc-271226 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAF53 (D-3): sc-271226. Western blot analysis of BAF53 expression in non-transfected: sc-117752 (A) and mouse BAF53 transfected: sc-118665 (B) 293T whole cell lysates.

BAF53 (B-1) - sc-137063 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAF53 (B-1): sc-137063. Western blot analysis of BAF53 expression in non-transfected 293T: sc-117752 (A), mouse BAF53 transfected 293T: sc-118664 (B) and Jurkat (C) whole cell lysates.

BAF53 (D-8) - sc-271177 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAF53 (D-8): sc-271177. Western blot analysis of BAF53 expression in non-transfected 293T: sc-117752 (A), mouse BAF53 transfected 293T: sc-118665 (B), K-562 (C), HeLa (D) and Ramos (E) whole cell lysates.

BAF53 (E-3) - sc-137062 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAF53 (E-3): sc-137062. Western blot analysis of BAF53 expression in non-transfected 293T: sc-117752 (A), mouse BAF53 transfected 293T: sc-118664 (B) and Jurkat (C) whole cell lysates.

BAF53 (G-2) - sc-137081 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAF53 (G-2): sc-137081. Western blot analysis of BAF53 expression in non-transfected 293T: sc-117752 (A), mouse BAF53 transfected 293T: sc-118664 (B) and Jurkat (C) whole cell lysates.

BAF53 (H-125) - sc-134542 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BAF53 (H-125): sc-134542. Western blot analysis of BAF53 expression in non-transfected: sc-117752 (A) and mouse BAF53 transfected: sc-118665 (B) 293T whole cell lysates.

BAF53 (C-13) - sc-47805 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BAF53 (N-19) - sc-47808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BAF53 (N-19): sc-47808. Western blot analysis of BAF53 expression in HeLa (A), Jurkat (B), SW480 (C), NIH/3T3 (D) and Sol8 (E) nuclear extracts and rat testis tissue extract (F).

Anti-ACTL6A antibody - ab189315 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue, labeling ACTL6A with ab189315 at 20 µg/ml.

Anti-ACTL6A antibody - ab130649 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ACTL6A antibody (ab130649) at 1/100 dilution + K562 cell line lysate at 35 µg

Anti-ACTL6A antibody [EPR7443] - ab131272 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7443
All lanes : Anti-ACTL6A antibody [EPR7443] (ab131272) at 1/1000 dilutionLane 1 : Ramos cell lysateLane 2 : K562 cell lysateLane 3 : HeLa cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit IgG at 1/2000 dilution

Anti-BAF53A antibody - ab64989 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BAF53A antibody (ab64989) at 1/500 dilutionLane 1 : Extracts from Jurkat cells with no immunising peptideLane 2 : Extracts from COLO205 cells with no immunising peptideLane 3 : Extracts from COLO205 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-BAF53A antibody - ab15718 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BAF53A antibody - ab13999 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-BAF53A antibody [N336B/83] - ab174941 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone N336B/83
All lanes : Anti-BAF53A antibody [N336B/83] (ab174941) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 3 : NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell LysateLane 4 : PC12 (Rat adrenal pheochromocytoma cell line) Whole Cell LysateLane 5 : Testis (Rat) Tissue Lysate - normal tissue (ab29388)Lysates/proteins at 20 µg per lane.SecondaryGoat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/10000 dilutionPerformed under reducing conditions.

Anti-BAF53A antibody - ChIP Grade - ab3882 from Abcam

Prices $398.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BAF53A antibody - ChIP Grade (ab3882) at 1/1000 dilutionLane 1 : TEV elution of Tip60-TAP clone 1 Lane 2 : TEV elution of Tip60-TAP clone 2Lane 3 : Total extract of Tip60-TAP clone 1Lane 4 : Total extract of Tip60-TAP clone 2Performed under reducing conditions.

Anti-BAF53 / ACTL6A Antibody (aa2-30, APC) - LS-C221360 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAF53 / ACTL6A Antibody (aa2-30, AP) - LS-C221359 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAF53 / ACTL6A Antibody (aa2-30, Biotin) - LS-C221365 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAF53 / ACTL6A Antibody (aa2-30, FITC) - LS-C221366 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAF53 / ACTL6A Antibody (aa2-30, Azide-free, HRP) - LS-C221367 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAF53 / ACTL6A Antibody (aa2-30, PE) - LS-C221368 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BAF53 / ACTL6A Antibody (aa35-84) - LS-C115969 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ACTL6A / BAF53A antibody LS-C115969 Western blot of Transfected 293T cell lysate.

Anti-BAF53 / ACTL6A Antibody - LS-C309315 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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