Gene Symbol | DLGAP5 |
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Entrez Gene | 9787 |
Alt Symbol | DLG7, HURP |
Species | Human |
Gene Type | protein-coding |
Description | discs, large (Drosophila) homolog-associated protein 5 |
Other Description | DAP-5|discs large homolog 7|discs, large homolog 7|disks large-associated protein 5|disks large-associated protein DLG7|hepatoma up-regulated protein |
Swissprots | B4DRM8 Q86T11 A8MTM6 Q15398 Q8NG58 |
Accessions | CBJ05774 CBJ21226 EAW80662 EAW80663 EAW80664 Q15398 AB076695 BAB97376 AI174844 AK291847 BAF84536 AK297480 BAG59901 AK299338 BAG61340 BC010658 AAH10658 BC016276 AAH16276 BM788630 BT007344 AAP36008 BX248255 CAD62583 D13633 BAA02797 DB448424 DB451654 XM_011537414 XP_011535716 XR_943566 NM_001146015 NP_001139487 NM_014750 NP_055565 |
Function | Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. {ECO:0000269|PubMed:12527899, ECO:0000269|PubMed:14699157, ECO:0000269|PubMed:15145941}. |
Subcellular Location | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells. |
Tissue Specificity | Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta. {ECO:0000269|PubMed:12527899}. |
Human HURP / DLGAP5 ELISA Kit (Sandwich ELISA) - LS-F7715 from LifeSpan Bioscience
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Human DLGAP5 ELISA Kit - abx151326 from Abbexa
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Discs, Large Homolog Associated Protein 5 (DLGAP5), Human, ELISA Kit - SEQ572Hu from ARP American Research Products
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discs, large (Drosophila) homolog-associated protein 5, ELISA Kit - MBS9338169 from MyBioSource
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ELISA Kit for Discs, Large Homolog Associated Protein 5 (DLGAP5) - SEQ572Hu from Uscn Life Science Inc.
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ELISA Kit for Discs, Large Homolog Associated Protein 5 (DLGAP5) - SEQ572Hu from Cloud-clone
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Human DLGAP5 ELISA Kit - abx572625 from Abbexa
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Human DLGAP5 ELISA Kit - E012043 from Biobool
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DLGAP5 ELISA Kit (Human) (OKCD02103) - OKCD02103 from Aviva Systems Biology
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Human Disks large-associated protein 5 (DLGAP5) ELISA Kit - AE47133HU from ARP American Research Products
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Discs, Large Homolog Associated Protein 5 (DLGAP5), ELISA Kit - MBS452948 from MyBioSource
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