Gene Symbol | DLGAP5 |
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Entrez Gene | 9787 |
Alt Symbol | DLG7, HURP |
Species | Human |
Gene Type | protein-coding |
Description | discs, large (Drosophila) homolog-associated protein 5 |
Other Description | DAP-5|discs large homolog 7|discs, large homolog 7|disks large-associated protein 5|disks large-associated protein DLG7|hepatoma up-regulated protein |
Swissprots | B4DRM8 Q86T11 A8MTM6 Q15398 Q8NG58 |
Accessions | CBJ05774 CBJ21226 EAW80662 EAW80663 EAW80664 Q15398 AB076695 BAB97376 AI174844 AK291847 BAF84536 AK297480 BAG59901 AK299338 BAG61340 BC010658 AAH10658 BC016276 AAH16276 BM788630 BT007344 AAP36008 BX248255 CAD62583 D13633 BAA02797 DB448424 DB451654 XM_011537414 XP_011535716 XR_943566 NM_001146015 NP_001139487 NM_014750 NP_055565 |
Function | Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. {ECO:0000269|PubMed:12527899, ECO:0000269|PubMed:14699157, ECO:0000269|PubMed:15145941}. |
Subcellular Location | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells. |
Tissue Specificity | Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta. {ECO:0000269|PubMed:12527899}. |
HURP / DLGAP5 Antibody Blocking Peptide - LS-E7118 from LifeSpan Bioscience
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HURP / DLGAP5 Antibody Blocking Peptide - LS-E7119 from LifeSpan Bioscience
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HURP / DLGAP5 Antibody Blocking Peptide - LS-E16851 from LifeSpan Bioscience
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DLG7-Antibody-Center-Blocking-Peptide - BP2810c from Abgent, a WuXi AppTec company
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DLG7-Antibody-N-term-Blocking-Peptide - BP2810a from Abgent, a WuXi AppTec company
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DLG7 Blocking Peptide - 33R-2820 from Fitzgerald
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HURP fusion protein - ag2667 from Proteintech Group
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Recombinant Discs, Large Homolog Associated Protein 5 (DLGAP5) - RPQ572Hu01 from Uscn Life Science Inc.
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Recombinant Discs, Large Homolog Associated Protein 5 (DLGAP5) - RPQ572Hu01 from Cloud-clone
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Recombinant Human Disks large-associated protein 5(DLGAP5) ,partial - CSB-YP622997HU CSB-EP622997HU CSB-BP622997HU CSB-MP622997HU from Cusabio
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DLG7/HURP Recombinant Protein Antigen - NBP1-87976PEP from Novus Biologicals
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DLGAP5 Peptide, Human - M34GP04346H from Creative Peptides
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DLGAP5 Antibody - SH-A11613 from Novatein Biosciences
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Disks large-associated protein 5 (DLGAP5), partial, Recombinant Protein - MBS1348719 from MyBioSource
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