DLGAP5

Gene Symbol DLGAP5
Entrez Gene 9787
Alt Symbol DLG7, HURP
Species Human
Gene Type protein-coding
Description discs, large (Drosophila) homolog-associated protein 5
Other Description DAP-5|discs large homolog 7|discs, large homolog 7|disks large-associated protein 5|disks large-associated protein DLG7|hepatoma up-regulated protein
Swissprots B4DRM8 Q86T11 A8MTM6 Q15398 Q8NG58
Accessions CBJ05774 CBJ21226 EAW80662 EAW80663 EAW80664 Q15398 AB076695 BAB97376 AI174844 AK291847 BAF84536 AK297480 BAG59901 AK299338 BAG61340 BC010658 AAH10658 BC016276 AAH16276 BM788630 BT007344 AAP36008 BX248255 CAD62583 D13633 BAA02797 DB448424 DB451654 XM_011537414 XP_011535716 XR_943566 NM_001146015 NP_001139487 NM_014750 NP_055565
Function Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. {ECO:0000269|PubMed:12527899, ECO:0000269|PubMed:14699157, ECO:0000269|PubMed:15145941}.
Subcellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
Tissue Specificity Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta. {ECO:0000269|PubMed:12527899}.

HURP (E-7) - sc-377004 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HURP (E-7): sc-377004. Western blot analysis of HURP expression in K-562 whole cell lysate.

HURP (G-14) - sc-68540 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HURP (G-14): sc-68540. Western blot analysis of HURP expression in non-transfected 293T: sc-117752 (A), human HURP transfected 293T: sc-111164 (B), MCF7 (C) and Caco-2 (D) whole cell lysates.

HURP (D-12) - sc-376760 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HURP (D-12): sc-376760. Western blot analysis of HURP expression in K-562 nuclear extract.

HURP (H-300) - sc-98724 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HURP (H-300): sc-98724. Western blot analysis of HURP expression in Ramos whole cell lysate.

HURP (D-15) - sc-68539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HURP (D-15): sc-68539. Western blot analysis of HURP expression in non-transfected 293T: sc-117752 (A), human HURP transfected 293T: sc-111164 (B), MCF7 (C) and Caco-2 (D) whole cell lysates.

Anti-HURP antibody - ab70744 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab70744 stained A549 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab70744, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-HURP antibody - ab70743 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling HURP with ab70743 at 1/200 (1µg/ml). Detection: DAB.

Anti-HURP antibody - ab84509 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84509, at 1/250 dilution, staining HURP in formalin-fixed, paraffin-embedded human basal cell carcinoma by Immunohistochemistry, using DAB staining.

Anti-HURP antibody - ab70742 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HURP antibody - ab80684 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HURP antibody (ab80684) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µgSecondaryHRP-conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-HURP antibody - ab26836 from Abcam

Host Chicken
Clonality Polyclonal

Anti-HURP antibody - Aminoterminal end - ab79870 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HURP antibody - Aminoterminal end (ab79870) at 1/50 dilution + RAMOS cell line lysate at 35 µg

Anti-HURP / DLGAP5 Antibody (aa1-30) - LS-C97297 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-DLG7 Antibody in Ramos cell line lysates (35 ug/lane). DLG7(arrow) was detected using the purified antibody.

Anti-HURP / DLGAP5 Antibody (aa200-250) - LS-C286429 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human HURP/DLG7 by Immunohistochemistry. Sample: FFPE section of human seminoma. Antibody: Affinity purified rabbit anti-HURP/DLG7 used at a dilution of 1:250.

Anti-HURP / DLGAP5 Antibody (aa228-258) - LS-C167434 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DLG7 Antibody IHC of formalin-fixed and paraffin-embedded hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-HURP / DLGAP5 Antibody - LS-C331976 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human stomach transfer using DLGAP5 antibody at dilution of 1:200 (x400 lens)

Anti-HURP / DLGAP5 Antibody (aa791-840) IHC-plus™ - LS-B5972 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-DLGAP5 / HURP antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5972 concentration 5 ug/ml.

Anti-HURP / DLGAP5 Antibody (aa200-250) - LS-C67687 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-HURP / DLGAP5 Antibody (aa150-200) - LS-C67686 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HURP / DLGAP5 Antibody (C-Terminus) - LS-C67688 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-HURP / DLGAP5 Antibody - LS-C96064 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Chicken
Clonality Polyclonal

Anti-HURP / DLGAP5 Antibody - LS-C193102 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HURP / DLGAP5 Antibody (aa150-200) - LS-C286212 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HURP / DLGAP5 Antibody (aa38-87) - LS-C80856 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-HURP / DLGAP5 Antibody (C-Terminus) - LS-C287700 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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