SLA2

Gene Symbol	SLA2
Entrez Gene	84174
Alt Symbol	C20orf156, MARS, SLAP-2, SLAP2
Species	Human
Gene Type	protein-coding
Description	Src-like-adaptor 2
Other Description	Src-like adapter protein-2|modulator of antigen receptor signaling|src-like-adapter 2
Swissprots	Q8WY18 Q5TH28 A8K648 E1P5U2 E1P5U1 Q9H6Q3 Q96QI4 Q5TH27 Q9H135
Accessions	EAW76116 EAW76117 EAW76118 EAW76119 Q9H6Q3 AF290985 AAL38197 AF290986 AAL38198 AF326353 AAL29204 AK025645 BAB15201 AK291513 BAF84202 BC042041 AAH42041 BF062179 BF510664 BQ052468 DA983348 XM_005260572 XP_005260629 NM_032214 NP_115590 NM_175077 NP_778252
Function	Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. {ECO:0000269|PubMed:11696592}.
Subcellular Location	Isoform 2: Cytoplasm {ECO:0000305}. Note=May be cytoplasmic and is not localized to membranes.
Tissue Specificity	Predominantly expressed in immune system, with highest levels in peripheral blood leukocytes. Expressed in spleen, thymus and lymph nodes. Expressed in T-cells as well as in monocytes, and at low level in B-cells. Also detected in placenta, prostate, skin, retina and colon.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SLA2 293T Cell Transient Overexpression Lysate(Denatured) - H00084174-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SLA2 overexpression lysate - LY406314 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SLA2 overexpression lysate - LY410277 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SLA2 293 Cell Lysate - 405288 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SLA2 293 Cell Lysate - 403880 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SLA2 Overexpression Lysate (Denatured) - H00084174-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

SLA2 Overexpression Lysate (Native) - NBL1-15998 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SLA2 (h): 293T Lysate - sc-115917 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

SLA2 Over-expression Lysate Product - GWB-5704B4 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

SLA2 Over-expression Lysate Product - GWB-350A5E from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

SLA2 Overexpression Lysate (Native) - NBP2-05079 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human SLA2 Knockdown Stable Cell Line - CSC-DC014296 from Creative biogene Category Cell Line Species Human

Search more