Gene Symbol | PIGW |
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Entrez Gene | 284098 |
Alt Symbol | Gwt1, HPMRS5 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class W |
Other Description | PIG-W|phosphatidylinositol glycan, class W|phosphatidylinositol-glycan biosynthesis class W protein |
Swissprots | Q7Z7B1 Q8N9G3 |
Accessions | EAW57563 EAW57564 Q7Z7B1 AB097818 BAC77021 AK094752 BAC04413 BC054025 BC144220 BC156433 AAI56434 BC160092 AAI60092 BC172479 AAI72479 XM_005257238 XP_005257295 XM_006725318 XP_006725381 XM_011524646 XP_011522948 XM_011546800 XP_011545102 NM_178517 NP_848612 |
Function | Required for the transport of GPI-anchored proteins to the plasma membrane (PubMed:24367057). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity). {ECO:0000250|UniProtKB:Q7TSN4, ECO:0000269|PubMed:24367057}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q7TSN4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q7TSN4}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
Human PIGW protein fragment - ab166161 from Abcam
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PIGW Antibody Blocking Peptide - LS-E17778 from LifeSpan Bioscience
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PIGW Antibody Blocking Peptide - LS-E17779 from LifeSpan Bioscience
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Recombinant Human PIGW Protein - H00284098-Q01 from Novus Biologicals
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PIGW peptide - orb218764 from Biorbyt
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Pigw Blocking Peptide - 33R-8528 from Fitzgerald
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PIGW Blocking Peptide - 33R-3893 from Fitzgerald
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PIGW Blocking Peptide - abx064095 from Abbexa
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PIGW - H00284098-Q01-10 from Acris Antibodies
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PIGW - H00284098-Q01-25 from Acris Antibodies
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Recombinant Human PIGW - PIGW-980H from Creative Biomart
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PIGW Blocking Peptide - CBP2901 from Cohesion Biosciences
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PIGW Peptide, Human - M34GP11771H from Creative Peptides
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