Gene Symbol | PIGW |
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Entrez Gene | 284098 |
Alt Symbol | Gwt1, HPMRS5 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class W |
Other Description | PIG-W|phosphatidylinositol glycan, class W|phosphatidylinositol-glycan biosynthesis class W protein |
Swissprots | Q7Z7B1 Q8N9G3 |
Accessions | EAW57563 EAW57564 Q7Z7B1 AB097818 BAC77021 AK094752 BAC04413 BC054025 BC144220 BC156433 AAI56434 BC160092 AAI60092 BC172479 AAI72479 XM_005257238 XP_005257295 XM_006725318 XP_006725381 XM_011524646 XP_011522948 XM_011546800 XP_011545102 NM_178517 NP_848612 |
Function | Required for the transport of GPI-anchored proteins to the plasma membrane (PubMed:24367057). Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity). {ECO:0000250|UniProtKB:Q7TSN4, ECO:0000269|PubMed:24367057}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q7TSN4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q7TSN4}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-W (E-15) - sc-165245 from Santa Cruz Biotechnology
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PIG-W (P-13) - sc-165248 from Santa Cruz Biotechnology
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PIG-W (H-22) - sc-133912 from Santa Cruz Biotechnology
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PIG-W (T-17) - sc-165249 from Santa Cruz Biotechnology
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Anti-PIGW antibody - ab105946 from Abcam
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Anti-PIGW Antibody - LS-C341009 from LifeSpan Bioscience
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Anti-PIGW Antibody (aa264-313) - LS-C82567 from LifeSpan Bioscience
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Anti-PIGW Antibody (aa221-270) - LS-C135222 from LifeSpan Bioscience
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PIGW Antibody - NBP1-60017 from Novus Biologicals
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PIGW Antibody - NBP2-13762 from Novus Biologicals
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PIGW Antibody (1D8) - H00284098-M05-100ug from Novus Biologicals
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Monoclonal Anti-PIGW antibody produced in mouse - SAB1412946 from Sigma-Aldrich
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Anti-PIGW antibody produced in rabbit - AV49147 from Sigma-Aldrich
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PIGW antibody - middle region (ARP49147_P050) - ARP49147_P050 from Aviva Systems Biology
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PIGW antibody - 70R-6939 from Fitzgerald
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Pigw antibody - 70R-8806 from Fitzgerald
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PIGW Antibody - abx007920 from Abbexa
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PIGW antibody - H00284098-M05 from Acris Antibodies
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Mouse Anti-Human PIGW - 101-11251 from RayBiotech
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PIGW Antibody - 30-511 from ProSci
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PIGW Antibody - GWB-MR422H from Genway Biotech
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Anti-PIGW monoclonal antibody - DCABH-12920 from Creative Diagnostics
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Anti-PIGW monoclonal antibody, clone 2E9 - DCABH-12921 from Creative Diagnostics
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PIGW, Polyclonal Antibody - MBS820906 from MyBioSource
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Anti-PIGW Antibody - CPA2901 from Cohesion Biosciences
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