FARS2

Gene Symbol FARS2
Entrez Gene 10667
Alt Symbol COXPD14, FARS1, HSPC320, PheRS, dJ520B18.2
Species Human
Gene Type protein-coding
Description phenylalanyl-tRNA synthetase 2, mitochondrial
Other Description dJ236A3.1 (phenylalanine-tRNA synthetase)|dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase))|phenylalanine tRNA ligase 2, mitochondrial|phenylalanine translase|phenylalanine--tRNA ligase, mitochondrial|phenylalanine-tRNA synthetase 1 (mitochondrial)
Swissprots B2R664 Q5TCS3 O95363 Q53F66 Q9P062 Q9NPY7 Q6FG29
Accessions EAW55179 O95363 AF097441 AAC83802 AF161438 AAF28998 AI338405 AK001146 AK223423 BAD97143 AK312454 BAG35361 BC020239 AAH20239 BC021112 AAH21112 BE792999 BG212473 BI761156 CN292346 CR542279 CAG47075 CR591198 XM_005248811 XP_005248868 XM_005248812 XP_005248869 XM_006714966 XP_006715029 XM_011514247 XP_011512549 XM_011514248 XP_011512550 XM_011514249 XP_011512551 XM_011514250 XP_011512552 XM_011514251 XP_011512553 XR_926026 XR_926027 XR_926028 NM_006567 NP_006558
Function Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins. {ECO:0000269|PubMed:19549855, ECO:0000269|PubMed:22833457}.
Subcellular Location Mitochondrion matrix {ECO:0000305}.
Top Pathways Aminoacyl-tRNA biosynthesis

FARS2-Over-expression-Lysate - LY10878a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag FARS2 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FARS2 gene

FARS2 293T Cell Transient Overexpression Lysate(Denatured) - H00010667-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

FARS2 overexpression lysate - LY416556 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

FARS2 293 Cell Lysate - 407732 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

FARS2 Overexpression Lysate (Native) - NBL1-10595 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: FARS2 Overexpression Lysate (Adult Normal) [NBL1-10595] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FARS2.

FARS2 Over-expression Lysate Product - GWB-136C99 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

FARS2 Overexpression Lysate (Denatured) - H00010667-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human FARS2 Knockdown Stable Cell Line - CSC-DC005535 from Creative biogene

Category Cell Line
Species Human
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