FARS2

Gene Symbol FARS2
Entrez Gene 10667
Alt Symbol COXPD14, FARS1, HSPC320, PheRS, dJ520B18.2
Species Human
Gene Type protein-coding
Description phenylalanyl-tRNA synthetase 2, mitochondrial
Other Description dJ236A3.1 (phenylalanine-tRNA synthetase)|dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase))|phenylalanine tRNA ligase 2, mitochondrial|phenylalanine translase|phenylalanine--tRNA ligase, mitochondrial|phenylalanine-tRNA synthetase 1 (mitochondrial)
Swissprots B2R664 Q5TCS3 O95363 Q53F66 Q9P062 Q9NPY7 Q6FG29
Accessions EAW55179 O95363 AF097441 AAC83802 AF161438 AAF28998 AI338405 AK001146 AK223423 BAD97143 AK312454 BAG35361 BC020239 AAH20239 BC021112 AAH21112 BE792999 BG212473 BI761156 CN292346 CR542279 CAG47075 CR591198 XM_005248811 XP_005248868 XM_005248812 XP_005248869 XM_006714966 XP_006715029 XM_011514247 XP_011512549 XM_011514248 XP_011512550 XM_011514249 XP_011512551 XM_011514250 XP_011512552 XM_011514251 XP_011512553 XR_926026 XR_926027 XR_926028 NM_006567 NP_006558
Function Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins. {ECO:0000269|PubMed:19549855, ECO:0000269|PubMed:22833457}.
Subcellular Location Mitochondrion matrix {ECO:0000305}.
Top Pathways Aminoacyl-tRNA biosynthesis

PheRS CRISPR/Cas9 KO Plasmid (h) - sc-411499 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PheRS HDR Plasmid (h) - sc-411499-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PheRS Double Nickase Plasmid (h) - sc-411499-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PheRS Double Nickase Plasmid (h2) - sc-411499-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PheRS CRISPR Activation Plasmid (h) - sc-411499-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PheRS CRISPR Activation Plasmid (h2) - sc-411499-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PheRS Lentiviral Activation Particles (h) - sc-411499-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PheRS Lentiviral Activation Particles (h2) - sc-411499-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PheRS siRNA (h) - sc-76115 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PheRS shRNA Plasmid (h) - sc-76115-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PheRS shRNA (h) Lentiviral Particles - sc-76115-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FARS2 RNAi - H00010667-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU133621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8484 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8484 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00676 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00676

FARS2 siRNA (Human) - CRH7274 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FARS2 - MBS8209504 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FARS2 (NM_006567.3) - SHH292438 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FARS2(NM_006567.3) - SHH049385 from Creative biogene

Category siRNA
Species Reactivities Human

FARS2 shRNA Plasmid (Human) - CHH7274 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FARS2 miRNA 3'UTR clone - MiUTR1H-03516 from Creative biogene

Species Reactivities Human
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