FARS2

Gene Symbol FARS2
Entrez Gene 10667
Alt Symbol COXPD14, FARS1, HSPC320, PheRS, dJ520B18.2
Species Human
Gene Type protein-coding
Description phenylalanyl-tRNA synthetase 2, mitochondrial
Other Description dJ236A3.1 (phenylalanine-tRNA synthetase)|dJ520B18.2 (FARS1 (phenylalanine-tRNA synthetase))|phenylalanine tRNA ligase 2, mitochondrial|phenylalanine translase|phenylalanine--tRNA ligase, mitochondrial|phenylalanine-tRNA synthetase 1 (mitochondrial)
Swissprots B2R664 Q5TCS3 O95363 Q53F66 Q9P062 Q9NPY7 Q6FG29
Accessions EAW55179 O95363 AF097441 AAC83802 AF161438 AAF28998 AI338405 AK001146 AK223423 BAD97143 AK312454 BAG35361 BC020239 AAH20239 BC021112 AAH21112 BE792999 BG212473 BI761156 CN292346 CR542279 CAG47075 CR591198 XM_005248811 XP_005248868 XM_005248812 XP_005248869 XM_006714966 XP_006715029 XM_011514247 XP_011512549 XM_011514248 XP_011512550 XM_011514249 XP_011512551 XM_011514250 XP_011512552 XM_011514251 XP_011512553 XR_926026 XR_926027 XR_926028 NM_006567 NP_006558
Function Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins. {ECO:0000269|PubMed:19549855, ECO:0000269|PubMed:22833457}.
Subcellular Location Mitochondrion matrix {ECO:0000305}.
Top Pathways Aminoacyl-tRNA biosynthesis

PheRS (F-9) - sc-166048 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PheRS (F-9): sc-166048. Western blot analysis of PheRS expression in non-transfected: sc-117752 (A) and mouse PheRS transfected: sc-122534 (B) 293T whole cell lysates.

PheRS (H-300) - sc-98544 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PheRS (H-300): sc-98544. Western blot analysis of PheRS expression in K-562 (A), CCRF-CEM (B) and T-47D (C) whole cell lysates.

PheRS (P-18) - sc-79271 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PheRS (T-19) - sc-79272 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FARS2 antibody - ab103399 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-FARS2 antibody (ab103399) at 1/100 dilution + WiDr cell line lysate at 12.5 µg

Anti-FARS2 antibody - ab140084 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded fetal kidney tissue labelling FARS2 with ab140084 at a dilution of 1/100

Anti-FARS2 antibody - ab68324 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-FARS2 antibody (ab68324) at 1/500 dilutionLane 1 : FARS2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-FARS2 Antibody (aa351-451) - LS-C307481 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FARS2 Antibody - LS-C307482 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-FARS2 Antibody - LS-C310323 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FARS2 Antibody (aa51-100) - LS-C40318 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
FARS2 antibody LS-C40318 was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.

Anti-FARS2 Antibody (aa286-451) - LS-C179102 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FARS2 Antibody - NBP1-57378 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FARS2 Antibody [NBP1-57378] - Transfected 293T, Antibody Titration: 5.0ug/ml

FARS2 Antibody - NBP1-85188 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FARS2 Antibody [NBP1-85188] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

FARS2 Antibody - NBP1-85187 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FARS2 Antibody [NBP1-85187] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

FARS2 Antibody - H00010667-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: FARS2 Antibody [H00010667-B01P] - Analysis of FARS2 expression in transfected 293T cell line by FARS2 polyclonal antibody. Lane 1: FARS2 transfected lysate(49.61 KDa). Lane 2: Non-transfected lysate.

FARS2 Antibody - H00010667-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: FARS2 Antibody [H00010667-B01] - analysis of FARS2 expression in transfected 293T cell line by FARS2 MaxPab polyclonal antibody (B01). Lane 1: FARS2 transfected lysate (52.40 KDa). Lane 2: Non-transfected lysate.

FARS2 Antibody (3F1) - H00010667-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3F1

FARS2 Antibody - H00010667-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

FARS2 Antibody - H00010667-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FARS2 antibody produced in rabbit - HPA018148 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FARS2: <B>Cat. No. HPA018148</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Anti-FARS2 antibody produced in rabbit - SAB1410120 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-FARS2: <B>Cat. No. SAB1410120</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~52.4 kDa using FARS2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-FARS2 antibody produced in rabbit - AV40669 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FARS2: <B>Cat. No. AV40669</B>: Immunohistochemistry of FARS2 in Human Muscle tissue with FARS2 antibody at 4-8 μg/mL.

Monoclonal Anti-FARS2, (C-terminal) antibody produced in mouse - SAB1403081 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3F1
<B>Immunoblotting</B><BR/>Monoclonal Anti-FARS2: <B>Cat. No. SAB1403081</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.2 kDa using immunogen protein lysate.

Anti-FARS2 antibody produced in mouse - SAB1407037 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-FARS2: <B>Cat. No. SAB1407037</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~49.6 kDa using FARS2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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