WARS

Gene Symbol	WARS
Entrez Gene	7453
Alt Symbol	GAMMA-2, IFI53, IFP53
Species	Human
Gene Type	protein-coding
Description	tryptophanyl-tRNA synthetase
Other Description	hWRS|interferon-induced protein 53|trpRS|tryptophan tRNA ligase 1, cytoplasmic|tryptophan--tRNA ligase, cytoplasmic
Swissprots	Q9UDL3 A6NID3 P23381 Q502Y0 A6NGN1 Q53XB6 P78535 Q9UDI5
Accessions	AAB39380 AAB39381 CAB94198 CAB94199 EAW81700 EAW81701 EAW81702 EAW81703 P23381 AK025487 AK056100 BAG51626 AK124668 AK130698 AK291141 BAF83830 AK300255 BAG62020 AV710027 BC017489 AAH17489 BC095453 AAH95453 BG717903 BM561448 BM834473 BX248006 CAD62335 M61715 AAA61298 M77804 AAA67324 X59892 CAA42545 X62570 CAA44450 XM_005268044 XP_005268101 XM_006720249 XP_006720312 XM_011537133 XP_011535435 XM_011537134 XP_011535436 XM_011537135 XP_011535437 XM_011537136 XP_011535438 XM_011537137 XP_011535439 NM_004184 NP_004175 NM_173701 NP_776049 NM_213645 NP_998810 NM_213646 NP_998811
Function	Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. {ECO:0000269|PubMed:11773625, ECO:0000269|PubMed:11773626, ECO:0000269|PubMed:1373391, ECO:0000269|PubMed:14630953}.
Subcellular Location	Cytoplasm.
Top Pathways	Aminoacyl-tRNA biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Tryptophanyl-tRNA synthetase, cytoplasmic, WARS, Human, ELISA Kit - E1748h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Tryptophanyl-tRNA synthetase, WARS, Human, ELISA Kit - CSB-E11789h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Tryptophanyl tRNA Synthetase, WARS, Human, ELISA Kit - E-EL-H1874 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.469 Range 0.781-50ng/mL

Tryptophanyl tRNA Synthetase, WARS, Rabbit, ELISA Kit - E-EL-RB1560 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Tryptophanyl tRNA Synthetase, WARS, Chicken, ELISA Kit - E-EL-Ch1818 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Tryptophanyl tRNA Synthetase, WARS, Porcine, ELISA Kit - E-EL-P0504 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Tryptophanyl tRNA Synthetase, WARS, Sheep, ELISA Kit - E-EL-S0707 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Tryptophanyl tRNA Synthetase, WARS, Guinea Pig, ELISA Kit - E-EL-GP0166 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Tryptophanyl tRNA Synthetase, WARS, Monkey, ELISA Kit - E-EL-MK1538 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

WARS (Human) IP-WB Antibody Pair - H00007453-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

WARS (Human) IP-WB Antibody Pair - H00007453-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

WARS (Human) Matched Antibody Pair - H00007453-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Human WARS(Tryptophanyl tRNA Synthetase) ELISA Kit - E-EL-H1874 from Elabscience Category ELISA Kit Sensitivity 0.47 ng/mL Range 0.78—50 ng/mL

Tryptophanyl-tRNA Synthetase, ELISA Kit - MBS494885 from MyBioSource Category ELISA Kit Prices $835.00 Sizes 96 tests Sensitivity The minimum detectable dose of WRS was determined by two standard deviations to the mean value of 20 blank samples. The minimum detectable dose of human WRS using a standard curve generated is 0.45 ng/ml.

tryptophanyl-tRNA synthetase, ELISA Kit - MBS703294 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human WARS is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.312 ng/ml-20 ng/ml.

WARS, ELISA Kit - MBS2510851 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of Human WARS is 0.469ng/mL Range 0.781-50ng/mL

WARS, ELISA Kit - MBS2506527 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

WARS, ELISA Kit - MBS2515236 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.375ng/mL Range 0.625-40ng/mL

WARS, ELISA Kit - MBS2506543 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.234ng/mL Range 0.391-25ng/mL

WARS, ELISA Kit - MBS2511665 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

WARS, ELISA Kit - MBS2500821 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

WARS, ELISA Kit - MBS2513116 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

ELISA Kit for Tryptophanyl tRNA Synthetase (WARS) - SEB748Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.62ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

ELISA Kit for Tryptophanyl tRNA Synthetase (WARS) - SEB748Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.064ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human tryptophanyl-tRNA synthetase,WARS ELISA Kit - CSB-E11789h from Cusabio Category ELISA Kit Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

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