WARS

Gene Symbol	WARS
Entrez Gene	7453
Alt Symbol	GAMMA-2, IFI53, IFP53
Species	Human
Gene Type	protein-coding
Description	tryptophanyl-tRNA synthetase
Other Description	hWRS|interferon-induced protein 53|trpRS|tryptophan tRNA ligase 1, cytoplasmic|tryptophan--tRNA ligase, cytoplasmic
Swissprots	Q9UDL3 A6NID3 P23381 Q502Y0 A6NGN1 Q53XB6 P78535 Q9UDI5
Accessions	AAB39380 AAB39381 CAB94198 CAB94199 EAW81700 EAW81701 EAW81702 EAW81703 P23381 AK025487 AK056100 BAG51626 AK124668 AK130698 AK291141 BAF83830 AK300255 BAG62020 AV710027 BC017489 AAH17489 BC095453 AAH95453 BG717903 BM561448 BM834473 BX248006 CAD62335 M61715 AAA61298 M77804 AAA67324 X59892 CAA42545 X62570 CAA44450 XM_005268044 XP_005268101 XM_006720249 XP_006720312 XM_011537133 XP_011535435 XM_011537134 XP_011535436 XM_011537135 XP_011535437 XM_011537136 XP_011535438 XM_011537137 XP_011535439 NM_004184 NP_004175 NM_173701 NP_776049 NM_213645 NP_998810 NM_213646 NP_998811
Function	Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. {ECO:0000269|PubMed:11773625, ECO:0000269|PubMed:11773626, ECO:0000269|PubMed:1373391, ECO:0000269|PubMed:14630953}.
Subcellular Location	Cytoplasm.
Top Pathways	Aminoacyl-tRNA biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tryptophanyl tRNA synthetase full length protein - ab185612 from Abcam Category Protein Source E. coli Species Human

Human Tryptophanyl tRNA synthetase full length protein - ab99263 from Abcam Category Protein Source E. coli Species Human

Human Tryptophanyl tRNA synthetase full length protein - ab185823 from Abcam Category Protein Source E. coli Species Human

Human Tryptophanyl tRNA synthetase full length protein - ab116687 from Abcam Category Protein Source E. coli Species Human

WARS Antibody Blocking Peptide - LS-E5595 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WARS Antibody Blocking Peptide - LS-E21427 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Tryptophanyl tRNA synthetase Partial Recombinant Protein - H00007453-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Tryptophanyl tRNA synthetase Recombinant Protein - H00007453-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Tryptophanyl tRNA synthetase Protein - NBP1-50843 from Novus Biologicals Category Protein Prices $309.00 Sizes 100 µg

WARS-Antibody-C-term-Blocking-Peptide - BP18122b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AGAP1 blocking peptide - GTX25299-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

GABA A Receptor gamma 2 (aa400-410) blocking peptide - GTX88118-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

GABA A Receptor gamma 2 (aa401-413) blocking peptide - GTX88178-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

WARS Protein (OPPA02385) - OPPA02385 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human WARS protein (His Tag) - orb139878 from Biorbyt Category Protein Prices $357.00, $748.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

Human WARS protein - orb180433 from Biorbyt Category Protein Prices $306.00, $400.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human WARS protein - orb90312 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Source E.coli Species Human

WARS Blocking Peptide - 33R-2465 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

WARS protein (His tag) - 80R-1389 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Human WARS Protein - abx069513 from Abbexa Category Protein Source E.coli Species Human

WARS / TrpRS (1-471, His-tag) - AR09564PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

WARS / TrpRS (1-471, His-tag) - AR09564PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

WARS / TrpRS - H00007453-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

WARS / TrpRS - H00007453-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

WARS / TrpRS - H00007453-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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