WARS

Gene Symbol WARS
Entrez Gene 7453
Alt Symbol GAMMA-2, IFI53, IFP53
Species Human
Gene Type protein-coding
Description tryptophanyl-tRNA synthetase
Other Description hWRS|interferon-induced protein 53|trpRS|tryptophan tRNA ligase 1, cytoplasmic|tryptophan--tRNA ligase, cytoplasmic
Swissprots Q9UDL3 A6NID3 P23381 Q502Y0 A6NGN1 Q53XB6 P78535 Q9UDI5
Accessions AAB39380 AAB39381 CAB94198 CAB94199 EAW81700 EAW81701 EAW81702 EAW81703 P23381 AK025487 AK056100 BAG51626 AK124668 AK130698 AK291141 BAF83830 AK300255 BAG62020 AV710027 BC017489 AAH17489 BC095453 AAH95453 BG717903 BM561448 BM834473 BX248006 CAD62335 M61715 AAA61298 M77804 AAA67324 X59892 CAA42545 X62570 CAA44450 XM_005268044 XP_005268101 XM_006720249 XP_006720312 XM_011537133 XP_011535435 XM_011537134 XP_011535436 XM_011537135 XP_011535437 XM_011537136 XP_011535438 XM_011537137 XP_011535439 NM_004184 NP_004175 NM_173701 NP_776049 NM_213645 NP_998810 NM_213646 NP_998811
Function Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. {ECO:0000269|PubMed:11773625, ECO:0000269|PubMed:11773626, ECO:0000269|PubMed:1373391, ECO:0000269|PubMed:14630953}.
Subcellular Location Cytoplasm.
Top Pathways Aminoacyl-tRNA biosynthesis

WARS 293T Cell Transient Overexpression Lysate(Denatured) - H00007453-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

WARS 293 Cell Lysate - 403962 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg

WARS 293 Cell Lysate - 401232 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Tryptophanyl tRNA synthetase Overexpression Lysate (Denatured) - H00007453-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: WARS transfected lysate (51.92 KDa) Lane 2: Non-transfected lysate.

Tryptophanyl tRNA synthetase Overexpression Lysate (Native) - NBL1-17772 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Tryptophanyl tRNA synthetase Overexpression Lysate (Adult Normal) [NBL1-17772] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Tryptophanyl tRNA synthetase.

Tryptophanyl tRNA synthetase Overexpression Lysate (Native) - NBL1-17773 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: Tryptophanyl tRNA synthetase Overexpression Lysate (Adult Normal) [NBL1-17773] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Tryptophanyl tRNA synthetase.

WARS Over-expression Lysate Product - GWB-D8158C from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

WARS Over-expression Lysate Product - GWB-CBC6B3 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Human WARS / TrpRS Insect Cell Lysate (WB positive control) - 14827-H07BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Tryptophanyl tRNA synthetase Overexpression Lysate (Denatured) - H00007453-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Human WARS Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175309 from Biorbyt

Category Cell Lysate
Prices $604.00
Sizes 300 μg
Species Human

Panoply™ Human WARS Knockdown Stable Cell Line - CSC-DC017374 from Creative biogene

Category Cell Line
Species Human
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