ADCK3

Gene Symbol ADCK3
Entrez Gene 56997
Alt Symbol ARCA2, CABC1, COQ10D4, COQ8, SCAR9
Species Human
Gene Type protein-coding
Description aarF domain containing kinase 3
Other Description aarF domain-containing protein kinase 3|atypical kinase ADCK3, mitochondrial|chaperone activity of bc1 complex-like, mitochondrial|chaperone, ABC1 activity of bc1 complex homolog|coenzyme Q8 homolog
Swissprots Q63HK0 Q9HBQ1 Q5T7A5 Q9NQ67 Q8NCJ6 Q8NI60
Accessions EAW69801 EAW69802 EAW69803 EAW69804 EAW69805 Q8NI60 AB073905 BAB91363 AF218003 AAG17245 AI888739 AJ278126 CAC00482 AK074693 BAC11143 AK090494 BAG52171 AK092784 AK126200 AK293571 BAG57042 AK297735 BAG60085 AK300537 BAG62245 AK301012 BAG62629 AL137511 BC005171 AAH05171 BC129930 AAI29931 BX648860 CAH56132 DA925261 XM_005273201 XP_005273258 XM_011544238 XP_011542540 XM_011544239 XP_011542541 XM_011544240 XP_011542542 XM_011544241 XP_011542543 NM_020247 NP_064632
Function Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144). Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway (PubMed:25498144). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144). {ECO:0000269|PubMed:25498144, ECO:0000305|PubMed:21296186, ECO:0000305|PubMed:25540914}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:11888884, ECO:0000269|PubMed:25498144}. Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255, ECO:0000305|PubMed:25216398}.
Tissue Specificity Widely expressed, with highest levels in adrenal gland, heart, pancreas, nasal mucosa, stomach, uterus and skeletal muscle. {ECO:0000269|PubMed:24270420}.

CABC1 (G-14) - sc-103417 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CABC1 (H-41) - sc-366173 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CABC1 (H-41): sc-366173. Western blot analysis of CABC1 expression in HeLa (A), Hep G2 (B), U-251 MG (C) and IMR-32 (D) whole cell lysates and mouse liver tissue extract (E).

CABC1 (687) - sc-100663 from Santa Cruz Biotechnology

Prices $295.00
Sizes 200 µl ascites
Host Mouse
Clonality Monoclonal
CABC1 (687): sc-100663. Western blot analysis of CABC1 expression in HeLa nuclear extract.

Anti-ADCK3 antibody - ab64816 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ADCK3 antibody (ab64816) at 1/500 dilutionLane 1 : Extracts from HepG2 cellsLane 2 : Extracts from mouse muscle cellsLane 3 : Extracts from mouse muscle cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-ADCK3 antibody - ab57525 from Abcam

Host Mouse
Clonality Monoclonal

Anti-ADCK3 antibody - ab57541 from Abcam

Host Mouse
Clonality Monoclonal

Anti-ADCK3 / CABC1 Antibody (clone 216CT7.5.1, APC) - LS-C221260 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 216CT7.5.1

Anti-ADCK3 / CABC1 Antibody (clone 216CT7.5.1, AP) - LS-C221256 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 216CT7.5.1

Anti-ADCK3 / CABC1 Antibody (clone 216CT7.5.1, Biotin) - LS-C221261 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 216CT7.5.1

Anti-ADCK3 / CABC1 Antibody (aa146-195) - LS-C81228 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ADCK3 / CABC1 Antibody (clone 216CT7.5.1, Azide-free, HRP) - LS-C221263 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 216CT7.5.1

Anti-ADCK3 / CABC1 Antibody (clone 216CT7.5.1, PE) - LS-C221264 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 216CT7.5.1

Anti-ADCK3 / CABC1 Antibody (aa472-521) - LS-C186686 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Thymus Tumor. ADCK3 antibody dilution 1.0 ug/ml.

Anti-ADCK3 / CABC1 Antibody (clone 216CT7.5.1, FITC) - LS-C221262 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 216CT7.5.1

Anti-ADCK3 / CABC1 Antibody (aa395-423, APC) - LS-C221596 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADCK3 / CABC1 Antibody (aa301-350) - LS-C119157 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HepG2/mouse muscle cells, using ADCK3 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-ADCK3 / CABC1 Antibody - LS-C168252 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
CABC1 antibody western blot of Widr cell line lysates (35 ug/lane). The CABC1 antibody detected the CABC1 protein (arrow).

Anti-ADCK3 / CABC1 Antibody (aa396-423) - LS-C164308 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Mouse Cabc1 Antibody western blot of mouse bladder tissue lysates (35 ug/lane). The Cabc1 antibody detected the Cabc1 protein (arrow).

Anti-ADCK3 / CABC1 Antibody (aa395-423, Biotin) - LS-C221597 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADCK3 / CABC1 Antibody (aa395-423, AP) - LS-C221595 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADCK3 / CABC1 Antibody (aa516-545) - LS-C98303 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-CABC1 Antibody (C-term D531) in 293 cell line lysates (35 ug/lane). CABC1 (arrow) was detected using the purified antibody.

Anti-ADCK3 / CABC1 Antibody (aa395-423, PE) - LS-C221600 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADCK3 / CABC1 Antibody (aa395-423, Azide-free, HRP) - LS-C221599 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ADCK3 / CABC1 Antibody - LS-C309675 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ADCK3 / CABC1 Antibody (aa395-423, FITC) - LS-C221598 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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