ADCK3

Gene Symbol	ADCK3
Entrez Gene	56997
Alt Symbol	ARCA2, CABC1, COQ10D4, COQ8, SCAR9
Species	Human
Gene Type	protein-coding
Description	aarF domain containing kinase 3
Other Description	aarF domain-containing protein kinase 3|atypical kinase ADCK3, mitochondrial|chaperone activity of bc1 complex-like, mitochondrial|chaperone, ABC1 activity of bc1 complex homolog|coenzyme Q8 homolog
Swissprots	Q63HK0 Q9HBQ1 Q5T7A5 Q9NQ67 Q8NCJ6 Q8NI60
Accessions	EAW69801 EAW69802 EAW69803 EAW69804 EAW69805 Q8NI60 AB073905 BAB91363 AF218003 AAG17245 AI888739 AJ278126 CAC00482 AK074693 BAC11143 AK090494 BAG52171 AK092784 AK126200 AK293571 BAG57042 AK297735 BAG60085 AK300537 BAG62245 AK301012 BAG62629 AL137511 BC005171 AAH05171 BC129930 AAI29931 BX648860 CAH56132 DA925261 XM_005273201 XP_005273258 XM_011544238 XP_011542540 XM_011544239 XP_011542541 XM_011544240 XP_011542542 XM_011544241 XP_011542543 NM_020247 NP_064632
Function	Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144). Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway (PubMed:25498144). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144). {ECO:0000269|PubMed:25498144, ECO:0000305|PubMed:21296186, ECO:0000305|PubMed:25540914}.
Subcellular Location	Mitochondrion {ECO:0000269|PubMed:11888884, ECO:0000269|PubMed:25498144}. Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255, ECO:0000305|PubMed:25216398}.
Tissue Specificity	Widely expressed, with highest levels in adrenal gland, heart, pancreas, nasal mucosa, stomach, uterus and skeletal muscle. {ECO:0000269|PubMed:24270420}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ADCK3 full length protein - ab163460 from Abcam Category Protein Source Wheat germ Species Human

Human ADCK3 protein fragment - ab163461 from Abcam Category Protein Source Wheat germ Species Human

Human ADCK3 protein fragment - ab191461 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

ADCK3 / CABC1 Antibody Blocking Peptide - LS-E3884 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADCK3 / CABC1 Antibody Blocking Peptide - LS-E8701 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADCK3 / CABC1 Antibody Blocking Peptide - LS-E17496 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CABC1 Protein - H00056997-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human CABC1 Protein - H00056997-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CABC1-Antibody-C-term-D531-Blocking-Peptide - BP7116b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CABC1 Blocking Peptide - 33R-2845 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CABC1 Blocking Peptide - abx063921 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine

CABC1 - H00056997-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CABC1 - H00056997-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CABC1 - H00056997-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CABC1 - H00056997-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CABC1 fusion protein - ag7509 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CABC1 fusion protein - Ag7612 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ADCK3, GST-tagged - ADCK3-97H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus Species Human

CABC1 Blocking Peptide - CBP2727 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine

Recombinant Human Chaperone activity of bc1 complex-like, mitochondrial(ADCK3) , - CSB-YP850918HU CSB-EP850918HU CSB-BP850918HU CSB-MP850918HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ADCK3 Protein - abx164332 from Abbexa Category Protein Species Human, Mouse, Rat

CABC1 Protein - abx164888 from Abbexa Category Protein Species Human, Mouse, Rat

Chaperone activity of bc1 complex-like, mitochondrial (ADCK3), partial, Recombinant Protein - MBS1324917 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CABC1-Antibody-N-term-Blocking-Peptide - BP7116a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ADCK3 Peptide, Human - M34GP00281H from Creative Peptides Category Peptide Source Synthetic. Species Human

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