ADCK3

Gene Symbol ADCK3
Entrez Gene 56997
Alt Symbol ARCA2, CABC1, COQ10D4, COQ8, SCAR9
Species Human
Gene Type protein-coding
Description aarF domain containing kinase 3
Other Description aarF domain-containing protein kinase 3|atypical kinase ADCK3, mitochondrial|chaperone activity of bc1 complex-like, mitochondrial|chaperone, ABC1 activity of bc1 complex homolog|coenzyme Q8 homolog
Swissprots Q63HK0 Q9HBQ1 Q5T7A5 Q9NQ67 Q8NCJ6 Q8NI60
Accessions EAW69801 EAW69802 EAW69803 EAW69804 EAW69805 Q8NI60 AB073905 BAB91363 AF218003 AAG17245 AI888739 AJ278126 CAC00482 AK074693 BAC11143 AK090494 BAG52171 AK092784 AK126200 AK293571 BAG57042 AK297735 BAG60085 AK300537 BAG62245 AK301012 BAG62629 AL137511 BC005171 AAH05171 BC129930 AAI29931 BX648860 CAH56132 DA925261 XM_005273201 XP_005273258 XM_011544238 XP_011542540 XM_011544239 XP_011542541 XM_011544240 XP_011542542 XM_011544241 XP_011542543 NM_020247 NP_064632
Function Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144). Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway (PubMed:25498144). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144). {ECO:0000269|PubMed:25498144, ECO:0000305|PubMed:21296186, ECO:0000305|PubMed:25540914}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:11888884, ECO:0000269|PubMed:25498144}. Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255, ECO:0000305|PubMed:25216398}.
Tissue Specificity Widely expressed, with highest levels in adrenal gland, heart, pancreas, nasal mucosa, stomach, uterus and skeletal muscle. {ECO:0000269|PubMed:24270420}.

CABC1 CRISPR/Cas9 KO Plasmid (h) - sc-408674 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CABC1 HDR Plasmid (h) - sc-408674-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CABC1 Double Nickase Plasmid (h) - sc-408674-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CABC1 Double Nickase Plasmid (h2) - sc-408674-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CABC1 CRISPR Activation Plasmid (h) - sc-408674-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CABC1 CRISPR Activation Plasmid (h2) - sc-408674-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CABC1 Lentiviral Activation Particles (h) - sc-408674-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CABC1 Lentiviral Activation Particles (h2) - sc-408674-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CABC1 siRNA (h) - sc-78990 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CABC1 shRNA Plasmid (h) - sc-78990-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CABC1 shRNA (h) Lentiviral Particles - sc-78990-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU150411 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0223 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0224 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0222 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2856 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2856 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ADCK3 siRNA (Human) - CRJ1280 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CABC1 RNAi - H00056997-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ADCK3 - MBS8225923 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADCK3 (NM_020247.4) - SHH232126 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CABC1(NM_020247.4) - SHG041029 from Creative biogene

Category siRNA
Species Reactivities Human

Human ADCK3 siRNA - orb271781 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADCK3 shRNA Plasmid (Human) - CHJ1280 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADCK3 miRNA 3'UTR clone - MiUTR1H-01569 from Creative biogene

Species Reactivities Human
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