ADCK3

Gene Symbol ADCK3
Entrez Gene 56997
Alt Symbol ARCA2, CABC1, COQ10D4, COQ8, SCAR9
Species Human
Gene Type protein-coding
Description aarF domain containing kinase 3
Other Description aarF domain-containing protein kinase 3|atypical kinase ADCK3, mitochondrial|chaperone activity of bc1 complex-like, mitochondrial|chaperone, ABC1 activity of bc1 complex homolog|coenzyme Q8 homolog
Swissprots Q63HK0 Q9HBQ1 Q5T7A5 Q9NQ67 Q8NCJ6 Q8NI60
Accessions EAW69801 EAW69802 EAW69803 EAW69804 EAW69805 Q8NI60 AB073905 BAB91363 AF218003 AAG17245 AI888739 AJ278126 CAC00482 AK074693 BAC11143 AK090494 BAG52171 AK092784 AK126200 AK293571 BAG57042 AK297735 BAG60085 AK300537 BAG62245 AK301012 BAG62629 AL137511 BC005171 AAH05171 BC129930 AAI29931 BX648860 CAH56132 DA925261 XM_005273201 XP_005273258 XM_011544238 XP_011542540 XM_011544239 XP_011542541 XM_011544240 XP_011542542 XM_011544241 XP_011542543 NM_020247 NP_064632
Function Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144). Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway (PubMed:25498144). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144). {ECO:0000269|PubMed:25498144, ECO:0000305|PubMed:21296186, ECO:0000305|PubMed:25540914}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:11888884, ECO:0000269|PubMed:25498144}. Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255, ECO:0000305|PubMed:25216398}.
Tissue Specificity Widely expressed, with highest levels in adrenal gland, heart, pancreas, nasal mucosa, stomach, uterus and skeletal muscle. {ECO:0000269|PubMed:24270420}.

CABC1-Over-expression-Lysate - LY11680a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CABC1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CABC1 gene

CABC1 293T Cell Transient Overexpression Lysate(Denatured) - H00056997-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

CABC1 293 Cell Lysate - 402410 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CABC1 Overexpression Lysate (Native) - NBL1-08622 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CABC1 Overexpression Lysate (Adult Normal) [NBL1-08622] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CABC1.

CABC1 Over-expression Lysate Product - GWB-2DDF94 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

CABC1 Overexpression Lysate (Denatured) - H00056997-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

CABC1 Overexpression Lysate (Denatured) - H00056997-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human ADCK3 Knockdown Stable Cell Line - CSC-DC000281 from Creative biogene

Category Cell Line
Species Human
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