ADAM12

Gene Symbol ADAM12
Entrez Gene 8038
Alt Symbol ADAM12-OT1, CAR10, MCMP, MCMPMltna, MLTN, MLTNA
Species Human
Gene Type protein-coding
Description ADAM metallopeptidase domain 12
Other Description disintegrin and metalloproteinase domain-containing protein 12|meltrin-alpha|metalloprotease-disintegrin 12 transmembrane
Swissprots Q6UWB0 Q5JRP0 O60470 Q5JRP1 Q6P9E3 O43184
Accessions CBH19188 EAW49205 EAW49206 EAW49207 EAW49208 EAW49209 O43184 AF023476 AAC08702 AF023477 AAC08703 AK055628 AK127856 AK291629 BAF84318 AY358878 AAQ89237 BC060804 AAH60804 BX098286 CB960379 DA027173 DA863951 DR004947 HG975387 KF444157 AGX93290 T91975 NM_001288973 NP_001275902 NM_001288974 NP_001275903 NM_001288975 NP_001275904 NM_003474 NP_003465 NM_021641 NP_067673
Function Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity). {ECO:0000250}.
Subcellular Location Isoform 3: Secreted {ECO:0000305}.
Tissue Specificity Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.

Human ADAM12 ORF Clone(NM_003474.4) - CDCL153105 from Creative Biomart

Species Human
Accession NM_003474.4

Human ADAM12 ORF clone(NM_003474.4) - CDCL182582 from Creative Biomart

Species Human
Accession NM_003474.4

Human ADAM12 transcript variant 1 Gene cDNA Clone (full-length ORF Clone) - HG10896-M from Sino Biological

Species Human
Accession NM_003474.4

ADAM12 - CL01070H02 from Elabscience

Species Human
Accession NM_021641.3

Human ADAM12 ORF clone(NM_003474.4) - CDCL182582 from Creative biogene

Species Human

Human ADAM12 ORF clone (NM_021641.3) - CDCR024408 from Creative biogene

Species Human
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