ADAM12

Gene Symbol ADAM12
Entrez Gene 8038
Alt Symbol ADAM12-OT1, CAR10, MCMP, MCMPMltna, MLTN, MLTNA
Species Human
Gene Type protein-coding
Description ADAM metallopeptidase domain 12
Other Description disintegrin and metalloproteinase domain-containing protein 12|meltrin-alpha|metalloprotease-disintegrin 12 transmembrane
Swissprots Q6UWB0 Q5JRP0 O60470 Q5JRP1 Q6P9E3 O43184
Accessions CBH19188 EAW49205 EAW49206 EAW49207 EAW49208 EAW49209 O43184 AF023476 AAC08702 AF023477 AAC08703 AK055628 AK127856 AK291629 BAF84318 AY358878 AAQ89237 BC060804 AAH60804 BX098286 CB960379 DA027173 DA863951 DR004947 HG975387 KF444157 AGX93290 T91975 NM_001288973 NP_001275902 NM_001288974 NP_001275903 NM_001288975 NP_001275904 NM_003474 NP_003465 NM_021641 NP_067673
Function Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity). {ECO:0000250}.
Subcellular Location Isoform 3: Secreted {ECO:0000305}.
Tissue Specificity Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas.

ADAM12 CRISPR/Cas9 KO Plasmid (h) - sc-402583 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAM12 HDR Plasmid (h) - sc-402583-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAM12 Double Nickase Plasmid (h) - sc-402583-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAM12 Double Nickase Plasmid (h2) - sc-402583-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAM12 CRISPR Activation Plasmid (h) - sc-402583-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAM12 CRISPR Activation Plasmid (h2) - sc-402583-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAM12 Lentiviral Activation Particles (h) - sc-402583-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAM12 Lentiviral Activation Particles (h2) - sc-402583-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADAM12 siRNA (h) - sc-41414 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADAM12 shRNA Plasmid (h) - sc-41414-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADAM12 shRNA (h) Lentiviral Particles - sc-41414-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADAM12 RNAi - H00008038-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU089561 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2159 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2159 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ADAM12 siRNA (Human) - CRH5350 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADAM12 RNAi - H00008038-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ADAM12 - MBS8214116 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADAM12 (NM_003474.4) - SHH231414 from Creative biogene

Category siRNA
Species Reactivities Human

ADAM12 shRNA Plasmid (Human) - CHH5350 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADAM12 miRNA 3'UTR clone - MiUTR3H-05260 from Creative biogene

Species Reactivities Human

ADAM12 miRNA 3'UTR clone - MiUTR3H-05261 from Creative biogene

Species Reactivities Human
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