AMER2

Gene Symbol	AMER2
Entrez Gene	219287
Alt Symbol	FAM123A
Species	Human
Gene Type	protein-coding
Description	APC membrane recruitment protein 2
Other Description	family with sequence similarity 123A|protein FAM123A
Swissprots	Q5RL80 Q5VX56 Q8N7J2 Q8N593 Q96NN5
Accessions	EAX08363 EAX08364 Q8N7J2 AK055049 BAB70845 AK055278 AK094378 AK098054 AK098343 BAC05288 AK098796 BAC05414 AL832586 AL832627 BC032653 AAH32653 BC041392 AAH41392 BC045677 BM680074 DA210701 XM_005266279 XP_005266336 XM_005266280 XP_005266337 XM_006719770 XP_006719833 NM_152704 NP_689917 NM_199138 NP_954589
Function	Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. {ECO:0000269|PubMed:22128170}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:22128170}; Peripheral membrane protein {ECO:0000269|PubMed:22128170}. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AMER2 Antibody Blocking Peptide - LS-E20060 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human APC membrane recruitment protein 2(FAM123A) - CSB-YP850820HU CSB-EP850820HU CSB-BP850820HU CSB-MP850820HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Family with sequence similarity 123A (FAM123A), transcript variant 2 (transcript variant 2) - TP319638 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

APC membrane recruitment protein 2 (FAM123A) , Recombinant Protein - MBS1460311 from MyBioSource Category Protein Prices $2,510.00, $2,510.00, $2,930.00, $2,930.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

FAM123A Recombinant Protein Antigen - NBP1-93907PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FAM123A Peptide, Human - M34GP05246H from Creative Peptides Category Peptide Source Synthetic. Species Human

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