AMER2

Gene Symbol	AMER2
Entrez Gene	219287
Alt Symbol	FAM123A
Species	Human
Gene Type	protein-coding
Description	APC membrane recruitment protein 2
Other Description	family with sequence similarity 123A|protein FAM123A
Swissprots	Q5RL80 Q5VX56 Q8N7J2 Q8N593 Q96NN5
Accessions	EAX08363 EAX08364 Q8N7J2 AK055049 BAB70845 AK055278 AK094378 AK098054 AK098343 BAC05288 AK098796 BAC05414 AL832586 AL832627 BC032653 AAH32653 BC041392 AAH41392 BC045677 BM680074 DA210701 XM_005266279 XP_005266336 XM_005266280 XP_005266337 XM_006719770 XP_006719833 NM_152704 NP_689917 NM_199138 NP_954589
Function	Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. {ECO:0000269|PubMed:22128170}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:22128170}; Peripheral membrane protein {ECO:0000269|PubMed:22128170}. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FAM123A CRISPR/Cas9 KO Plasmid (h) - sc-404231 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A HDR Plasmid (h) - sc-404231-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A Double Nickase Plasmid (h) - sc-404231-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A Double Nickase Plasmid (h2) - sc-404231-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A CRISPR Activation Plasmid (h) - sc-404231-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A CRISPR Activation Plasmid (h2) - sc-404231-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A Lentiviral Activation Particles (h) - sc-404231-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A Lentiviral Activation Particles (h2) - sc-404231-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A siRNA (h) - sc-105346 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FAM123A shRNA Plasmid (h) - sc-105346-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FAM123A shRNA (h) Lentiviral Particles - sc-105346-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN8149 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8149 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07756 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr07756

AMER2 siRNA (Human) - CRJ6368 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

AMER2 - MBS8201677 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

FAM123A CRISPR/Cas9 KO Plasmid (h2) - sc-404231-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FAM123A HDR Plasmid (h2) - sc-404231-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human FAM123A (NM_199138.1) - SHH289365 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human FAM123A(NM_152704.2) - SHH045805 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human FAM123A(NM_199138.1) - SHH045823 from Creative biogene Category siRNA Species Reactivities Human

AMER2 shRNA Plasmid (Human) - CHJ6368 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

FAM123A miRNA 3'UTR clone - MiUTR1H-03408 from Creative biogene Species Reactivities Human

FAM123A miRNA 3'UTR clone - MiUTR1H-03409 from Creative biogene Species Reactivities Human

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