CBX3

Gene Symbol	CBX3
Entrez Gene	11335
Alt Symbol	HECH, HP1-GAMMA, HP1Hs-gamma
Species	Human
Gene Type	protein-coding
Description	chromobox homolog 3
Other Description	HP1 gamma homolog|chromobox homolog 3 (HP1 gamma homolog, Drosophila)|chromobox protein homolog 3|heterochromatin protein 1 homolog gamma|heterochromatin protein HP1 gamma|heterochromatin-like protein 1|modifier 2 protein
Swissprots	Q9P0Z6 Q9BVS3 Q99409 Q96CD7 Q13185
Accessions	EAL24235 EAW93842 EAW93843 EAW93844 EAW93845 EAW93846 Q13185 AB030905 BAA83340 AF086270 AF136630 AAF62370 AL542267 BC000954 AAH00954 BC014380 AAH14380 BX647444 BX648807 CD514780 CV575477 DB565723 EU831928 ACE87369 EU832023 ACE86685 U26312 AAB48101 XM_005249611 XP_005249668 XM_005249612 XP_005249669 NM_007276 NP_009207 NM_016587 NP_057671
Function	Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
Subcellular Location	Nucleus {ECO:0000305}. Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CBX3 / HP1 Gamma ELISA Kit (Sandwich ELISA) - LS-F6792 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-CBX3 / HP1 Gamma (Ser93) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1713 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat CBX3 / HP1 Gamma ELISA Kit (Cell-Based ELISA) - LS-F2057 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Rabbit anti-CBX3 Antibody, Affinity Purified - PLA0160 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Human Chromobox Homolog 3 ELISA Kit - abx151066 from Abbexa Category ELISA Kit Sensitivity 0.056 ng/ml Range 0.156 ng/ml - 10 ng/ml

Chromobox Homolog 3, CBX3, Human, ELISA Kit - E-EL-H0736 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Chromobox Homolog 3 (CBX3), Human, ELISA Kit - SEC363Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.056ng/mL Range 0.156-10 ng/mL

Chromobox Homolog 3, CBX3, Mouse, ELISA Kit - E-EL-M0286 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Chromobox Homolog 3, CBX3, Rabbit, ELISA Kit - E-EL-RB0710 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Chromobox Homolog 3, CBX3, Chicken, ELISA Kit - E-EL-Ch1977 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Chromobox Homolog 3, CBX3, Porcine, ELISA Kit - E-EL-P1994 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Chromobox Homolog 3, CBX3, Sheep, ELISA Kit - E-EL-S0425 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Chromobox Homolog 3, CBX3, Monkey, ELISA Kit - E-EL-MK1715 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human CBX3 ELISA Kit - HC0615 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine CBX3 ELISA Kit - AC0615 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Chromobox Homolog 3, ELISA Kit - MBS102874 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromobox Homolog 3, ELISA Kit - MBS042717 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromobox Homolog 3, ELISA Kit - MBS734701 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Chromobox Homolog 3 (CBX3), ELISA Kit - MBS2019766 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.055ng/mL. Range 0.156-10ng/mL

HP1gamma Colorimetric Cell-Based ELISA Kit - CB5341 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

HP1gamma (Phospho-Ser93) Colorimetric Cell-Based ELISA Kit - CBP1792 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Human CBX3(Chromobox Homolog 3) ELISA Kit - E-EL-H0736 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

CBX3, ELISA Kit - MBS2503972 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156--10ng/mL

CBX3, ELISA Kit - MBS2514767 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

CBX3, ELISA Kit - MBS2508906 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

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