CBX3

Gene Symbol	CBX3
Entrez Gene	11335
Alt Symbol	HECH, HP1-GAMMA, HP1Hs-gamma
Species	Human
Gene Type	protein-coding
Description	chromobox homolog 3
Other Description	HP1 gamma homolog|chromobox homolog 3 (HP1 gamma homolog, Drosophila)|chromobox protein homolog 3|heterochromatin protein 1 homolog gamma|heterochromatin protein HP1 gamma|heterochromatin-like protein 1|modifier 2 protein
Swissprots	Q9P0Z6 Q9BVS3 Q99409 Q96CD7 Q13185
Accessions	EAL24235 EAW93842 EAW93843 EAW93844 EAW93845 EAW93846 Q13185 AB030905 BAA83340 AF086270 AF136630 AAF62370 AL542267 BC000954 AAH00954 BC014380 AAH14380 BX647444 BX648807 CD514780 CV575477 DB565723 EU831928 ACE87369 EU832023 ACE86685 U26312 AAB48101 XM_005249611 XP_005249668 XM_005249612 XP_005249669 NM_007276 NP_009207 NM_016587 NP_057671
Function	Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
Subcellular Location	Nucleus {ECO:0000305}. Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HP1 gamma peptide (74-87) - ab45826 from Abcam Category Peptide Prices $290.00 Sizes 100 µg Species Human

Human HP1 gamma (phospho S93) peptide - ab45386 from Abcam Category Peptide Species Human

Human HP1 gamma full length protein - ab124548 from Abcam Category Protein Source E. coli Species Human

Human HP1 gamma full length protein - ab88011 from Abcam Category Protein Source Saccharomyces cerevisiae Species Human

Human HP1 gamma peptide - ab51840 from Abcam Category Peptide

Mouse HP1 gamma peptide - ab15025 from Abcam Category Peptide

CBX3 / HP1 Gamma Antibody Blocking Peptide - LS-E12355 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CBX3 / HP1 Gamma Antibody Blocking Peptide - LS-E12354 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CBX3 / HP1 Gamma Antibody Blocking Peptide - LS-E25966 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CBX3 Recombinant Protein - H00011335-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CBX3 Protein - NBP1-99065 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

CBX3-Antibody-Center-Blocking-peptide - BP13718c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CBX3-Antibody-N-term-Blocking-Peptide - BP8916a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HP1 gamma blocking peptide - GTX89454-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Human CBX3 protein - orb168046 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

CBX3 Blocking Peptide - 33R-9942 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CBX3 Blocking Peptide - 33R-2551 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CBX3 protein (His tag) - 80R-2199 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

Human CBX3 Protein - abx060011 from Abbexa Category Protein Source Yeast Species Human

Human Chromobox Homolog 3 Protein - abx065890 from Abbexa Category Protein Source E.coli Species Human

HP1 gamma Peptide - AC21-0793-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CBX3 (1-183, His-tag) - AR50281PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CBX3 (1-183, His-tag) - AR50281PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CBX3 - H00011335-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CBX3 - H00011335-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Search more