CBX3

Gene Symbol	CBX3
Entrez Gene	11335
Alt Symbol	HECH, HP1-GAMMA, HP1Hs-gamma
Species	Human
Gene Type	protein-coding
Description	chromobox homolog 3
Other Description	HP1 gamma homolog|chromobox homolog 3 (HP1 gamma homolog, Drosophila)|chromobox protein homolog 3|heterochromatin protein 1 homolog gamma|heterochromatin protein HP1 gamma|heterochromatin-like protein 1|modifier 2 protein
Swissprots	Q9P0Z6 Q9BVS3 Q99409 Q96CD7 Q13185
Accessions	EAL24235 EAW93842 EAW93843 EAW93844 EAW93845 EAW93846 Q13185 AB030905 BAA83340 AF086270 AF136630 AAF62370 AL542267 BC000954 AAH00954 BC014380 AAH14380 BX647444 BX648807 CD514780 CV575477 DB565723 EU831928 ACE87369 EU832023 ACE86685 U26312 AAB48101 XM_005249611 XP_005249668 XM_005249612 XP_005249669 NM_007276 NP_009207 NM_016587 NP_057671
Function	Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
Subcellular Location	Nucleus {ECO:0000305}. Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CBX3 293 Cell Lysate - 407526 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Species Drosophila

CBX3 293 Cell Lysate - 406669 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Species Drosophila

CBX3 Overexpression Lysate (Native) - NBL1-08748 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CBX3 Overexpression Lysate (Native) - NBL1-08749 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CBX3 Over-expression Lysate Product - GWB-FB5F43 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

CBX3 Over-expression Lysate Product - GWB-208D62 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

CBX3-knockout Cell lysate - LC810325 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human CBX3 Knockdown Stable Cell Line - CSC-DC002438 from Creative biogene Category Cell Line Species Human

Human CBX3 Knockout Cell Line-HeLa - CSC-RT0621 from Creative biogene Category Cell Line Species Human

CBX3 KO Cell Lysate-HeLa - CLKO-0127 from Creative biogene Category Cell Lysate

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