CBX3

Gene Symbol CBX3
Entrez Gene 11335
Alt Symbol HECH, HP1-GAMMA, HP1Hs-gamma
Species Human
Gene Type protein-coding
Description chromobox homolog 3
Other Description HP1 gamma homolog|chromobox homolog 3 (HP1 gamma homolog, Drosophila)|chromobox protein homolog 3|heterochromatin protein 1 homolog gamma|heterochromatin protein HP1 gamma|heterochromatin-like protein 1|modifier 2 protein
Swissprots Q9P0Z6 Q9BVS3 Q99409 Q96CD7 Q13185
Accessions EAL24235 EAW93842 EAW93843 EAW93844 EAW93845 EAW93846 Q13185 AB030905 BAA83340 AF086270 AF136630 AAF62370 AL542267 BC000954 AAH00954 BC014380 AAH14380 BX647444 BX648807 CD514780 CV575477 DB565723 EU831928 ACE87369 EU832023 ACE86685 U26312 AAB48101 XM_005249611 XP_005249668 XM_005249612 XP_005249669 NM_007276 NP_009207 NM_016587 NP_057671
Function Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
Subcellular Location Nucleus {ECO:0000305}. Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). {ECO:0000305}.

HP1γ CRISPR/Cas9 KO Plasmid (h) - sc-417205 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1γ HDR Plasmid (h) - sc-417205-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1γ Double Nickase Plasmid (h) - sc-417205-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1γ Double Nickase Plasmid (h2) - sc-417205-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1γ CRISPR Activation Plasmid (h) - sc-417205-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1γ CRISPR Activation Plasmid (h2) - sc-417205-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1γ Lentiviral Activation Particles (h) - sc-417205-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1γ Lentiviral Activation Particles (h2) - sc-417205-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HP1γ siRNA (h) - sc-35589 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HP1γ shRNA Plasmid (h) - sc-35589-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HP1γ shRNA (h) Lentiviral Particles - sc-35589-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CBX3 RNAi - H00011335-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU113471 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5427 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5427 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08574 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08574

CBX3 siRNA (Human) - CRH7762 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CBX3 RNAi - H00011335-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CBX3 - MBS8206776 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CBX3 (NM_007276.4) - SHH255509 from Creative biogene

Category siRNA
Species Reactivities Human

Human CBX3 siRNA - orb268264 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CBX3 shRNA Plasmid (Human) - CHH7762 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CBX3 miRNA 3'UTR clone - MiUTR3H-06837 from Creative biogene

Species Reactivities Human

CBX3 miRNA 3'UTR clone - MiUTR3H-06838 from Creative biogene

Species Reactivities Human
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