TXN

Gene Symbol	TXN
Entrez Gene	7295
Alt Symbol	TRDX, TRX, TRX1
Species	Human
Gene Type	protein-coding
Description	thioredoxin
Other Description	ADF|ATL-derived factor|SASP|TXN delta 3|surface-associated sulphydryl protein|thioredoxin delta 3
Swissprots	Q96KI3 O60744 B1ALW1 Q9UDG5 P10599 Q53X69
Accessions	AAN33187 CAA38410 EAW59059 EAW59060 P10599 AF065241 AAC17430 AF085844 AF276919 AAF86466 AF313911 AAG34699 AK289508 BAF82197 AW160756 AY004872 AAF87085 BC003377 AAH03377 BC054866 AAH54866 BQ774337 BX647247 CR407665 CAG28593 D28376 BAA05742 J04026 AAA74596 JQ313905 AFH41799 X77584 CAA54687 NM_001244938 NP_001231867 NM_003329 NP_003320
Function	Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
Subcellular Location	Nucleus. Cytoplasm. Secreted. Note=Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F4703 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 12.4 pg/ml Range 31.25-2000 pg/ml

Rat TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F4704 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.114 ng/ml Range 31.25-2000 pg/ml

Mouse TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F4705 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 31.25 pg/ml Range 31.25-2000 pg/ml

Spinach TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F6127 from LifeSpan Bioscience Category ELISA Kit Prices $920.00 Sizes 1 plate Sensitivity 0.124 ng/ml Range 31.25-2000 pg/ml

Human TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F2917 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 156 pg/ml Range 31.25-2000 pg/ml

Human TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F12753 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 31.25-2000 pg/ml

Pig TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F12755 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 3.12 Range 31.25-2000 pg/ml

Rat TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F12754 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 1.56 Range 31.25-2000 pg/ml

Mouse TXN / Thioredoxin / TRX ELISA Kit (Sandwich ELISA) - LS-F12756 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 1.56 Range 31.25-2000 pg/ml

Human Thioredoxin ELISA kit - 55R-27417 from Fitzgerald Category ELISA Kit Prices $645.00 Sizes 96 wells

Thioredoxin (Trx), Human, ELISA Kit - SEA702Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 14.2pg/mL Range 31.2-2,000pg/mL

Thioredoxin, Human, ELISA Kit - 27417 from ARP American Research Products Category ELISA Kit Prices $733.00 Sizes 96 t Range 3.91 ~ 250 ng/mL

Thioredoxin, Human, ELISA Kit - E01T0336 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 2.5-50 ng/mL

Thioredoxin, Trx, Human, ELISA Kit - CSB-E09728h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 1.17 ng/ml Range 4.68 ng/ml-300 ng/ml

Thioredoxin, TXN, Human, ELISA Kit - E0702h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.78-50 ng/mL

Thioredoxin, Trx, Human, ELISA Kit - E-EL-H1727 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Thioredoxin, Trx, Mouse, ELISA Kit - E-EL-M1134 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Thioredoxin, TRX, Rat, ELISA Kit - E-EL-R0954 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Thioredoxin, Trx, Rabbit, ELISA Kit - E-EL-RB1395 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Thioredoxin, Trx, Chicken, ELISA Kit - E-EL-Ch1653 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Thioredoxin, Trx, Porcine, ELISA Kit - E-EL-P0370 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Thioredoxin, Trx, Guinea Pig, ELISA Kit - E-EL-GP0194 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Thioredoxin (Trx), Spinach, ELISA Kit - SEA702Pl from ARP American Research Products Category ELISA Kit Prices $920.00 Sizes 96 t Sensitivity 0.124ng/mL Range 0.312-20ng/mL

Thioredoxin, Trx, Monkey, ELISA Kit - E-EL-MK1880 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Thioredoxin (Trx), Human, CLIA Kit - SCA702Hu from ARP American Research Products Category CLIA Kit Prices $840.00 Sizes 96 t Sensitivity 21.7pg/mL Range 62.5-4,000pg/mL

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