TXN

Gene Symbol TXN
Entrez Gene 7295
Alt Symbol TRDX, TRX, TRX1
Species Human
Gene Type protein-coding
Description thioredoxin
Other Description ADF|ATL-derived factor|SASP|TXN delta 3|surface-associated sulphydryl protein|thioredoxin delta 3
Swissprots Q96KI3 O60744 B1ALW1 Q9UDG5 P10599 Q53X69
Accessions AAN33187 CAA38410 EAW59059 EAW59060 P10599 AF065241 AAC17430 AF085844 AF276919 AAF86466 AF313911 AAG34699 AK289508 BAF82197 AW160756 AY004872 AAF87085 BC003377 AAH03377 BC054866 AAH54866 BQ774337 BX647247 CR407665 CAG28593 D28376 BAA05742 J04026 AAA74596 JQ313905 AFH41799 X77584 CAA54687 NM_001244938 NP_001231867 NM_003329 NP_003320
Function Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
Subcellular Location Nucleus. Cytoplasm. Secreted. Note=Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus.

Trx CRISPR/Cas9 KO Plasmid (h) - sc-400746 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx HDR Plasmid (h) - sc-400746-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx Double Nickase Plasmid (h) - sc-400746-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx Double Nickase Plasmid (h2) - sc-400746-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx CRISPR Activation Plasmid (h) - sc-400746-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx CRISPR Activation Plasmid (h2) - sc-400746-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx Lentiviral Activation Particles (h) - sc-400746-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx Lentiviral Activation Particles (h2) - sc-400746-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx siRNA (h) - sc-106984 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Trx shRNA Plasmid (h) - sc-106984-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Trx shRNA (h) Lentiviral Particles - sc-106984-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU112621 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22300 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22300 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TXN siRNA (Human) - CRH4989 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Thioredoxin RNAi - H00007295-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TXN - MBS8203248 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Trx CRISPR/Cas9 KO Plasmid (h2) - sc-400746-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Trx HDR Plasmid (h2) - sc-400746-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human TXN (NM_003329.3) - SHH438156 from Creative biogene

Category siRNA
Species Reactivities Human

Human TRX siRNA - orb265491 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TXN shRNA Plasmid (Human) - CHH4989 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TXN miRNA 3'UTR clone - MiUTR3H-02206 from Creative biogene

Species Reactivities Human
Search more