Bax

Gene Symbol	Bax
Entrez Gene	12028
Alt Symbol	-
Species	Mouse
Gene Type	protein-coding
Description	BCL2-associated X protein
Other Description	apoptosis regulator BAX
Swissprots	Q07813
Accessions	AAL73334 BAA82406 EDL22857 EDL22858 Q07813 AK013298 BAB28776 AK149994 BAE29222 AK159233 BAE34919 AV355155 AY095934 AAM34436 BC018228 AAH18228 BC053380 AAH53380 BY308683 CJ078904 L22472 AAA03622 XM_006540584 XP_006540647 XM_011250780 XP_011249082 NM_007527 NP_031553
Function	Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production. {ECO:0000269|PubMed:21060336, ECO:0000269|PubMed:8358790}.
Subcellular Location	Isoform Gamma: Cytoplasm {ECO:0000250}.
Tissue Specificity	Expressed in a wide variety of tissues.
Top Pathways	Sphingolipid signaling pathway, Viral carcinogenesis, Non-alcoholic fatty liver disease (NAFLD), Apoptosis, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Apoptosis regulator BAX, Mouse, ELISA Kit - E03A1782 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Bcl-2 associated X protein, Bax, Mouse, ELISA Kit - CSB-E17114m from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 1.95 pg/ml Range 7.8 pg/ml-500 pg/ml

BCL2-associated X protein, ELISA Kit - MBS706061 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of mouse Bax is typically less than 1.95 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 7.8 pg/ml -500 pg/ml.

Mouse Bcl-2 associated X protein, Bax ELISA Kit - CSB-E17114m from Cusabio Category ELISA Kit Sensitivity 1.95 pg/ml Range 7.8 pg/ml-500 pg/ml

ELISA Kit for Bcl2 Associated X Protein (Bax) - SEB343Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 25.2pg/mL. Range 62.5-4000pg/mL The standard curve concentrations used for the ELISA's were 4000pg/mL, 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL

Mouse Apoptosis regulator BAX ELISA Kit - abx254935 from Abbexa Category ELISA Kit Range 31.2 pg/ml - 2000 pg/ml

Mouse Apoptosis regulator BAX ELISA Kit - EKE52197 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Range 31.2-2000 pg/mL

Bax ELISA Kit (Mouse) (OKEH04827) - OKEH04827 from Aviva Systems Biology Category ELISA Kit Prices $425.00 Sizes 96 wells Sensitivity < 15.6 pg/mL Range 31.2 - 2,000 pg/mL

Mouse Apoptosis regulator BAX ELISA Kit - EK3225 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Range 31.2-2000 pg/mL

anti-Bax antibody - ARG65612 from Arigo Biolaboratories Category ELISA Kit

Bcl2 Associated X Protein (Bax), ELISA Kit - MBS451519 from MyBioSource Category ELISA Kit Prices $410.00, $540.00, $2,380.00, $4,620.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <24.5pg/mL Range 62.5-4000pg/mL

Apoptosis regulator BAX, ELISA Kit - MBS9427059 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Range 31.2-2000 pg/mL

Apoptosis regulator BAX, ELISA Kit - MBS2882510 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 31.2 pg/mL-2000 pg/mL

Mouse BAX ELISA Kit - orb408798 from Biorbyt Category ELISA Kit Sensitivity 1.95 pg/ml Range 7.8 pg/ml-500 pg/ml

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