Bax

Gene Symbol Bax
Entrez Gene 12028
Alt Symbol -
Species Mouse
Gene Type protein-coding
Description BCL2-associated X protein
Other Description apoptosis regulator BAX
Swissprots Q07813
Accessions AAL73334 BAA82406 EDL22857 EDL22858 Q07813 AK013298 BAB28776 AK149994 BAE29222 AK159233 BAE34919 AV355155 AY095934 AAM34436 BC018228 AAH18228 BC053380 AAH53380 BY308683 CJ078904 L22472 AAA03622 XM_006540584 XP_006540647 XM_011250780 XP_011249082 NM_007527 NP_031553
Function Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production. {ECO:0000269|PubMed:21060336, ECO:0000269|PubMed:8358790}.
Subcellular Location Isoform Gamma: Cytoplasm {ECO:0000250}.
Tissue Specificity Expressed in a wide variety of tissues.
Top Pathways Sphingolipid signaling pathway, Viral carcinogenesis, Non-alcoholic fatty liver disease (NAFLD), Apoptosis, Tuberculosis

Bax CRISPR/Cas9 KO Plasmid (m) - sc-419292 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bax HDR Plasmid (m) - sc-419292-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bax Double Nickase Plasmid (m) - sc-419292-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bax Double Nickase Plasmid (m2) - sc-419292-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bax CRISPR Activation Plasmid (m) - sc-419292-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bax CRISPR Activation Plasmid (m2) - sc-419292-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bax Lentiviral Activation Particles (m) - sc-419292-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bax Lentiviral Activation Particles (m2) - sc-419292-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Bax siRNA (m) - sc-29213 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Bax shRNA Plasmid (m) - sc-29213-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Bax shRNA (m) Lentiviral Particles - sc-29213-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN27415 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27415 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BAX siRNA (Mouse) - CRM0345 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

BAX - MBS8216065 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse BAX (NM_007527.3) - SHH245014 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Bax(NM_007527.3) - SHG091585 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse BAX siRNA - orb279821 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

BAX shRNA Plasmid (Mouse) - CHM0345 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

BAX miRNA 3'UTR clone - MiUTR1M-01980 from Creative biogene

Species Reactivities Mouse
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