BMI1

Gene Symbol	BMI1
Entrez Gene	648
Alt Symbol	FLVI2/BMI1, PCGF4, RNF51
Species	Human
Gene Type	protein-coding
Description	BMI1 proto-oncogene, polycomb ring finger
Other Description	B lymphoma Mo-MLV insertion region 1 homolog|BMI1 polycomb ring finger oncogene|BMI1 polycomb ring finger proto-oncogene|flvi-2/bmi-1|murine leukemia viral (bmi-1) oncogene homolog|polycomb complex protein BMI-1|polycomb group RING finger protein 4|polycomb group protein Bmi1|ring finger protein 51
Swissprots	Q96F37 P35226 Q5T8Z3 Q16030
Accessions	EAW86148 EAW86150 EAW86151 EAW86154 P35226 AI274830 BC011652 AAH11652 BE008203 BT019450 AAV38257 CR456911 CAG33192 DB161566 DB225488 L13689 AAA19873 NM_005180 NP_005171
Function	Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. {ECO:0000269|PubMed:16359901, ECO:0000269|PubMed:16714294, ECO:0000269|PubMed:16882984}.
Subcellular Location	Nucleus. Cytoplasm.
Top Pathways	MicroRNAs in cancer, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Bmi1 full length protein - ab114169 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Bmi1 full length protein - ab134860 from Abcam Category Protein Prices $345.00 Sizes 50 µg Source E. coli Species Human

Human Bmi1 peptide - ab39733 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Human Bmi1 peptide - ab86660 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

BMI1 / PCGF4 Antibody Blocking Peptide - LS-E30217 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

BMI1 / PCGF4 Antibody Blocking Peptide - LS-E12113 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BMI1 / PCGF4 Antibody Blocking Peptide - LS-E11904 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BMI1 / PCGF4 Antibody Blocking Peptide - LS-E6976 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BMI-1 Blocking Peptide - NB110-40823PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Recombinant Human BMI-1 Protein - H00000648-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BMI-1 Blocking Peptide - NBP1-76685PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

BMI-1 Peptide - P1122 from Novus Biologicals Category Peptide Species Human

BMI1-Antibody-C-term-Blocking-peptide - BP2513b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human BMI1 protein - orb245172 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

BMI1 Blocking Peptide - 33R-11004 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

PCGF4 Blocking Peptide - 33R-9239 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human PCGF4 Protein - abx068635 from Abbexa Category Protein Source E.coli Species Human

BMI-1 / RNF51 - H00000648-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BMI-1 / RNF51 - H00000648-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BMI-1 / RNF51 Control Peptide - AP30158CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Polycomb Group Ring Finger Protein 4 (PCGF4), Human - 20-9108 from ARP American Research Products Category Protein Prices $389.00 Sizes 50 µg Source E.coli Species Human

BMI-1 Peptide - 3755P from ProSci Category Peptide Species Human

BMI1 fusion protein - Ag1286 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

BMI1 fusion protein - ag21284 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Bmi1 Peptide - 350547 from ABBIOTEC Category Peptide Prices $50.00 Sizes 100 µg

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