GDNF

Gene Symbol	GDNF
Entrez Gene	2668
Alt Symbol	ATF1, ATF2, HFB1-GDNF, HSCR3
Species	Human
Gene Type	protein-coding
Description	glial cell derived neurotrophic factor
Other Description	ATF|astrocyte-derived trophic factor|glial cell line-derived neurotrophic factor
Swissprots	Q9UD33 Q9UD32 B7WPK7 Q9UP97 Q6FH33 Q9UP67 O95986 Q9UMV2 O95449 O95448 Q96L44 P39905
Accessions	AAA67910 AAB33493 AAB33494 AAC98782 CAA05074 CBY79817 EAW55963 EAW55964 P39905 AF053748 AAD43139 AJ001897 CAA05075 AJ001898 CAA05076 AJ001899 CAA05077 AJ001900 CAA05078 AY052832 AAL11017 BC008580 AAH08580 BC069119 AAH69119 BC069369 AAH69369 BC128108 AAI28109 BC128109 AAI28110 CR541923 CAG46721 DQ235474 XM_011514028 XP_011512330 XM_011514029 XP_011512331 XM_011514030 XP_011512332 NM_000514 NP_000505 NM_001190468 NP_001177397 NM_001190469 NP_001177398 NM_199231 NP_954701 NM_199234 NM_001278098 NP_001265027
Function	Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. {ECO:0000269|PubMed:8493557}.
Subcellular Location	Secreted {ECO:0000269|PubMed:9811930}.
Tissue Specificity	In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change. {ECO:0000269|PubMed:22081608, ECO:0000269|PubMed:7867768}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GDNF-Over-expression-Lysate - LY10123a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

GDNF overexpression lysate - LY403701 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GDNF overexpression lysate - LY424672 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GDNF overexpression lysate - LY424999 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

GDNF 293 Cell Lysate - 403187 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

GDNF Overexpression Lysate (Native) - NBL1-11032 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

GDNF Overexpression Lysate (Native) - NBP2-09073 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

GDNF Overexpression Lysate (Native) - NBP2-09015 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

GDNF Overexpression Lysate (Native) - NBL1-11031 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

GDNF Over-expression Lysate Product - GWB-C33B29 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

GDNF Over-expression Lysate Product - GWB-C01AD5 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Human GDNF HEK293 Cell Lysate (WB positive control) - 10561-HNCHL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human GDNF Human Cells Transfected Lysate (positive control) (denatured) - orb174140 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

GDNF Overexpression Lysate (Denatured) - H00002668-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

GDNF Overexpression Lysate (Denatured) - H00002668-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human GDNF Knockdown Stable Cell Line - CSC-DC006196 from Creative biogene Category Cell Line Species Human

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