ADI1

Gene Symbol	ADI1
Entrez Gene	55256
Alt Symbol	APL1, ARD, Fe-ARD, HMFT1638, MTCBP1, Ni-ARD, SIPL, mtnD
Species	Human
Gene Type	protein-coding
Description	acireductone dioxygenase 1
Other Description	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase|MT1-MMP cytoplasmic tail-binding protein-1|acireductone dioxygenase (Fe(2+)-requiring)|acireductone dioxygenase (Ni(2+)-requiring)|membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1|submergence induced protein 2|submergence-induced protein-like factor
Swissprots	Q68CK2 Q6ZSF7 Q53QD3 Q9BV57 Q57YV7 Q96P85 Q9NV57 Q53HW3 Q7Z512 D6W4Y3
Accessions	AAX82038 AAY24022 CAR81477 CAS91493 EAX01064 EAX01065 Q9BV57 AB073609 BAD38646 AB158319 BAD10866 AF087863 AAP97173 AF403478 AAL25800 AK001775 BAA91901 AK127473 BAC86996 AK222467 BAD96187 AK225278 BC001467 AAH01467 CB129674 DA559726 HQ448743 ADQ33221 XM_005264696 XP_005264753 NM_001306077 NP_001293006 NM_018269 NP_060739
Function	Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line. {ECO:0000255|HAMAP- Rule:MF_03154, ECO:0000269|PubMed:11602742, ECO:0000269|PubMed:15938715}.
Subcellular Location	Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14.
Tissue Specificity	Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:11602742, ECO:0000269|PubMed:14718544}.
Top Pathways	Cysteine and methionine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ADI1 full length protein - ab140543 from Abcam Category Protein Prices $297.00 Sizes 100 µg Source E. coli Species Human

ADI1 / ARD Antibody Blocking Peptide - LS-E4226 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADI1 / ARD Antibody Blocking Peptide - LS-E24083 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADI1 / ARD Antibody Blocking Peptide - LS-E24084 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADI1 Recombinant Protein - H00055256-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human ADI1 Protein - NBP2-22667 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Species Human

ADI1-Antibody-Center-Blocking-Peptide - BP16495c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MTCBP-1 Recombinant Protein - GTX48003-PRO from GeneTex Category Protein Prices $329.00 Sizes 50 μg Source E. coli Species Human

Human ADI1 protein - orb167858 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

ADI1 protein (His tag) - 80R-2679 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

ADI1 / MTCBP1 (1-179, His-tag) - AR50799PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ADI1 / MTCBP1 (1-179, His-tag) - AR50799PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ADI1 / MTCBP1 - H00055256-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ADI1 / MTCBP1 - H00055256-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ADI1, 1-179aa, Human, His tag, E.coli - 01-P1975 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

MTCBP-1 Recombinant Protein - XW-RP3154 from ProSci Category Protein Prices $475.00 Sizes 100 µg Source E. coli Species Human

ADI1 fusion protein - Ag7274 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ADI1 fusion protein - Ag7303 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

ADI1 Human - ENPS-707 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Acireductone Dioxygenase 1, T7-tagged - ADI1-392H from Creative Biomart Category Protein Source E.Coli.

Recombinant Human ADI1, T7 -tagged - ADI1-27097TH from Creative Biomart Category Protein Source E. coli

Recombinant Human ADI1, His-tagged - ADI1-7531H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human ADI1, GST-tagged - ADI1-9423H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(ADI1) - CSB-YP861145HU CSB-EP861145HU CSB-BP861145HU CSB-MP861145HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(LMJF_20_0970) - CSB-YP709001LOG CSB-EP709001LOG CSB-BP709001LOG CSB-MP709001LOG from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Leishmania

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