BCL10

Gene Symbol	BCL10
Entrez Gene	8915
Alt Symbol	CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
Species	Human
Gene Type	protein-coding
Description	B-cell CLL/lymphoma 10
Other Description	B-cell lymphoma/leukemia 10|CARD containing molecule enhancing NF-kB|CARD-containing apoptotic signaling protein|CARD-containing molecule enhancing NF-kappa-B|CARD-containing proapoptotic protein|CED-3/ICH-1 prodomain homologous E10-like regulator|cCARMEN|caspase-recruiting domain-containing protein|cellular homolog of vCARMEN|cellular-E10|hCLAP|mammalian CARD-containing adapter molecule E10
Swissprots	O95999 Q5VUF1
Accessions	AAD24918 EAW73208 O95999 AF057700 AAD15800 AF082283 AAC99767 AF100338 AAD16428 AF105066 AAF06894 AF127386 AAD32597 AF134395 AAD39147 AJ006288 CAA06955 AK098790 AK291346 BAF84035 BC053617 AAH53617 BI831624 BX647306 CA420027 CA443148 CB126730 EF189176 ABN09569 XM_005271311 XP_005271368 XM_011542397 XP_011540699 XM_011542398 XP_011540700 XM_011542399 XP_011540701 NM_003921 NP_003912
Function	Involved in adaptive immune response (PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF- kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101). {ECO:0000269|PubMed:18264101, ECO:0000269|PubMed:25365219}.
Subcellular Location	Cytoplasm, perinuclear region {ECO:0000269|PubMed:17287217}. Membrane raft {ECO:0000269|PubMed:17287217}. Note=Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts.
Tissue Specificity	Ubiquitous.
Top Pathways	T cell receptor signaling pathway, B cell receptor signaling pathway, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat BCL10 / BCL-10 ELISA Kit (Sandwich ELISA) - LS-F10919 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

B-Cell CLL/Lymphoma 10, Human, ELISA Kit - E01B0574 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 5.0-100ng/ml

B-cell lymphoma/leukemia 10, BCL10, Human, ELISA Kit - E9627h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t

B-cell Leukemia/Lymphoma 10, Bcl-10, Human, ELISA Kit - E-EL-H0557 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

B-Cell CLL/Lymphoma 10, Bcl10, Mouse, ELISA Kit - E-EL-M0681 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

B-Cell Leukemia/Lymphoma 10, BCL10, Rat, ELISA Kit - E-EL-R0093 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

B-cell Leukemia/Lymphoma 10, Bcl-10, Rabbit, ELISA Kit - E-EL-RB0139 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

B-cell Leukemia/Lymphoma 10, Bcl-10, Chicken, ELISA Kit - E-EL-Ch0591 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

B-cell Leukemia/Lymphoma 10, Bcl-10, Porcine, ELISA Kit - E-EL-P1162 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

B-cell Leukemia/Lymphoma 10, Bcl-10, Sheep, ELISA Kit - E-EL-S0598 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

B-cell Leukemia/Lymphoma 10, Bcl-10, Guinea Pig, ELISA Kit - E-EL-GP1251 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

B-cell Leukemia/Lymphoma 10, Bcl-10, Monkey, ELISA Kit - E-EL-MK0687 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human Bcl10 ELISA Kit - HB0581 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine Bcl10 ELISA Kit - AB0581 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

B Cell CLL/Lymphoma 10, ELISA Kit - MBS731024 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

BCL10, ELISA Kit - MBS2512959 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Bcl10, ELISA Kit - MBS2512195 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563-100ng/mL

Human Bcl-10(B-cell Lymphoma/Leukemia 10) ELIS Kit - E-EL-H0557 from Elabscience Category ELISA Kit Sensitivity 0.94 ng/mL Range 1.56—100 ng/mL

B-Cell CLL/Lymphoma 10, ELISA Kit - MBS748032 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

B-Cell CLL/Lymphoma 10, ELISA Kit - MBS723203 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

B-Cell Cll/Lymphoma 10, ELISA Kit - MBS040965 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

B-Cell CLL/Lymphoma 10, ELISA Kit - MBS727560 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

B-Cell Cll/Lymphoma 10, ELISA Kit - MBS030987 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

B-Cell Cll/Lymphoma 10, ELISA Kit - MBS050444 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

B-Cell Cll/Lymphoma 10, ELISA Kit - MBS027159 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more