FBXO4

Gene Symbol FBXO4
Entrez Gene 26272
Alt Symbol FBX4
Species Human
Gene Type protein-coding
Description F-box protein 4
Other Description F-box only protein 4|F-box protein Fbx4
Swissprots Q86VT8 Q9UK98 Q68CU8 Q9UKT5
Accessions EAW56019 EAW56020 Q9UKT5 AF129534 AAF04468 AF176703 AAF03703 AK001003 BAA91463 AK024075 BAG51262 AU143782 BC040011 BC048098 AAH48098 CR749719 CAH18486 HQ447994 ADQ32475 XM_006714470 XP_006714533 XM_011514026 XP_011512328 XM_011514027 XP_011512329 NM_001297437 NP_001284366 NM_012176 NP_036308 NM_033484 NP_277019
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1. {ECO:0000269|PubMed:10531035, ECO:0000269|PubMed:16275645, ECO:0000269|PubMed:18598945, ECO:0000269|PubMed:20159592, ECO:0000269|PubMed:20181953}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Ubiquitin mediated proteolysis

FBXO4 (D-9) - sc-376372 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FBXO4 (D-9): sc-376372. Western blot analysis of FBXO4 expression in Y79 whole cell lysate.

FBXO4 (E-16) - sc-162828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FBXO4 (H-300) - sc-134721 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FBXO4 (H-300): sc-134721. Western blot analysis of FBXO4 expression in non-transfected: sc-117752 (A) and mouse FBXO4 transfected: sc-120218 (B) 293T whole cell lysates.

FBXO4 (K-12) - sc-162829 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FBXO4 antibody - ab176179 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FBXO4 antibody (ab176179) at 1/1000 dilution + Y79 cell lysate at 35 µg

Anti-FBXO4 antibody - ab67024 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-FBXO4 antibody (ab67024) at 1/500 dilutionLane 1 : Transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugated at 1/5000 dilution

Anti-FBXO4 / FBX4 Antibody (aa231-260, AP) - LS-C257121 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody (aa231-260, APC) - LS-C257122 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody (aa231-260, Biotin) - LS-C257123 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody (aa231-260, FITC) - LS-C257124 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody (C-Terminus) - LS-C102003 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FBXO4 antibody LS-C102003 Western blot of 293T cell lysate.

Anti-FBXO4 / FBX4 Antibody (C-Terminus) - LS-C110761 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FBXO4 antibody LS-C110761 Western blot of OVCAR-3 cell lysate.

Anti-FBXO4 / FBX4 Antibody (aa231-260, Azide-free, HRP) - LS-C257125 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody (aa231-260, PE) - LS-C257126 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody - LS-C307977 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody (aa225-251) - LS-C166087 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of FBXO4 Antibody in Y79 cell line lysates (35 ug/lane). FBXO4 (arrow) was detected using the purified antibody.

Anti-FBXO4 / FBX4 Antibody - LS-C307978 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FBXO4 / FBX4 Antibody - LS-C310339 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody - LS-C310340 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody (aa231-260) - LS-C329543 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FBXO4 / FBX4 Antibody (N-Terminus) - LS-C18995 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry staining of NIH-3T3 cells using anti-FBX4. Cells were fixed in methanol/acetone followed by incubation with anti-FBX4 at a 1:300 dilution.

Anti-FBXO4 / FBX4 Antibody (aa250-262) IHC-plus™ - LS-B6496 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-FBXO4 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6496 concentration 2.5 ug/ml.

FBXO4 Antibody - NBP2-16450 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FBXO4 Antibody [NBP2-16450] - Sample (30 ug of whole cell lysate) A: A431 B: HeLa 10% SDS PAGE gel, diluted at 1:2000.

FBXO4 Antibody - NBP2-21608 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FBXO4 Antibody [NBP2-21608] - Sample (30 ug of whole cell lysate) A: HL-60 10% SDS PAGE gel, diluted at 1:5000.

FBXO4 Antibody - H00026272-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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