FBXO4

Gene Symbol FBXO4
Entrez Gene 26272
Alt Symbol FBX4
Species Human
Gene Type protein-coding
Description F-box protein 4
Other Description F-box only protein 4|F-box protein Fbx4
Swissprots Q86VT8 Q9UK98 Q68CU8 Q9UKT5
Accessions EAW56019 EAW56020 Q9UKT5 AF129534 AAF04468 AF176703 AAF03703 AK001003 BAA91463 AK024075 BAG51262 AU143782 BC040011 BC048098 AAH48098 CR749719 CAH18486 HQ447994 ADQ32475 XM_006714470 XP_006714533 XM_011514026 XP_011512328 XM_011514027 XP_011512329 NM_001297437 NP_001284366 NM_012176 NP_036308 NM_033484 NP_277019
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1. {ECO:0000269|PubMed:10531035, ECO:0000269|PubMed:16275645, ECO:0000269|PubMed:18598945, ECO:0000269|PubMed:20159592, ECO:0000269|PubMed:20181953}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Ubiquitin mediated proteolysis

Human FBXO4 full length protein - ab161961 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161961 on a 12.5% SDS-PAGE stained with Coomassie Blue.

FBXO4 / FBX4 Antibody Blocking Peptide - LS-E27316 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FBXO4 / FBX4 Antibody Blocking Peptide - LS-E15879 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FBXO4 / FBX4 Antibody Blocking Peptide - LS-E15878 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FBXO4 / FBX4 Antibody Blocking Peptide - LS-E10049 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human FBXO4 Protein - H00026272-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

FBXO4-Antibody-Center-Blocking-Peptide - BP9295c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

FBXO4 blocking peptide - GTX88175-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Rat, Bovine

FBXO4 Blocking Peptide - 33R-4632 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

FBXO4 Blocking Peptide - 33R-9277 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

FBXO4 Peptide - AC21-2139-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

FBXO4 - H00026272-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

FBXO4 - H00026272-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

FBXO4 Peptide - 42-543P from ProSci

Category Peptide

FBX4 fusion protein - ag4829 from Proteintech Group

Category Protein
Species Human

FBX4 fusion protein - ag5013 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human F-box only protein 4(FBXO4) - CSB-YP891538HU CSB-EP891538HU CSB-BP891538HU CSB-MP891538HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

FBXO4 (transcript variant 1) - TP308458 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
FBXO4

FBXO4, Peptide - MBS428298 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Mouse, Rat, Dog, Bovine

FBXO4, Peptide - MBS427232 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Bovine

FBXO4 Peptide, Human - M34GP05606H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

F-box only protein 4 (FBXO4), Recombinant Protein - MBS1302289 from MyBioSource

Category Protein
Prices $1,155.00, $1,155.00, $1,385.00, $1,385.00, $1,850.00, $1,850.00, $2,315.00, $2,315.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

FBXO4 Recombinant Protein Antigen - NBP2-58623PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
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