FBXO4

Gene Symbol FBXO4
Entrez Gene 26272
Alt Symbol FBX4
Species Human
Gene Type protein-coding
Description F-box protein 4
Other Description F-box only protein 4|F-box protein Fbx4
Swissprots Q86VT8 Q9UK98 Q68CU8 Q9UKT5
Accessions EAW56019 EAW56020 Q9UKT5 AF129534 AAF04468 AF176703 AAF03703 AK001003 BAA91463 AK024075 BAG51262 AU143782 BC040011 BC048098 AAH48098 CR749719 CAH18486 HQ447994 ADQ32475 XM_006714470 XP_006714533 XM_011514026 XP_011512328 XM_011514027 XP_011512329 NM_001297437 NP_001284366 NM_012176 NP_036308 NM_033484 NP_277019
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1. {ECO:0000269|PubMed:10531035, ECO:0000269|PubMed:16275645, ECO:0000269|PubMed:18598945, ECO:0000269|PubMed:20159592, ECO:0000269|PubMed:20181953}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Ubiquitin mediated proteolysis

FBXO4-Over-expression-Lysate - LY11755a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag FBXO4 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FBXO4 gene

FBXO4 293T Cell Transient Overexpression Lysate(Denatured) - H00026272-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

FBXO4 293 Cell Lysate - 401907 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

FBXO4 Overexpression Lysate (Denatured) - H00026272-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

FBXO4 Overexpression Lysate (Native) - NBL1-10635 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: FBXO4 Overexpression Lysate (Adult Normal) [NBL1-10635] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FBXO4.

FBXO4 Over-expression Lysate Product - GWB-C24553 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

FBXO4 Overexpression Lysate (Denatured) - H00026272-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human FBXO4 Knockdown Stable Cell Line - CSC-DC005606 from Creative biogene

Category Cell Line
Species Human
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