CNGA4

Gene Symbol	CNGA4
Entrez Gene	1262
Alt Symbol	CNCA2, CNG-4, CNG4, CNG5, CNGB2, OCNC2, OCNCBETA, OCNCb
Species	Human
Gene Type	protein-coding
Description	cyclic nucleotide gated channel alpha 4
Other Description	CNG channel alpha-4|cyclic nucleotide gated channel beta 2|cyclic nucleotide-gated cation channel alpha-4
Swissprots	Q8IV77
Accessions	CAD42376 CAD42377 EAW68736 Q8IV77 AK122736 AK302551 BAG63820 BC040277 AAH40277 BC106935 BC106936 BC160170 AAI60170 DB238337 XM_006718145 XP_006718208 XM_011519899 XP_011518201 NM_001037329 NP_001032406
Function	Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity). {ECO:0000250}.
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Top Pathways	Olfactory transduction, cAMP signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CNGA4 full length protein - ab158148 from Abcam Category Protein Source Wheat germ Species Human

CNGA4 Antibody Blocking Peptide - LS-E1238 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CNGA4 Protein - H00001262-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CNGA4-Antibody-N-term-Blocking-peptide - BP11811a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CNGA4 - H00001262-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CNGA4 - H00001262-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CNGA4 fusion protein - ag16129 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CNGA4 fusion protein - ag17481 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CNGA4 Peptide, Human - M34GP03360H from Creative Peptides Category Peptide Source Synthetic. Species Human

human CNGA4 protein - orb54674 from Biorbyt Category Protein Prices $2,066.00, $3,562.00, $5,432.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Cyclic nucleotide-gated cation channel alpha-4 (CNGA4), Recombinant Protein - MBS7011836 from MyBioSource Category Protein Prices $1,370.00, $2,355.00, $3,565.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

CNGA4 Recombinant Protein (Human) (OPCA05294) - OPCA05294 from Aviva Systems Biology Category Protein Species Human

Recombinant Human Cyclic nucleotide-gated cation channel alpha-4 (CNGA4) - RPC20810 from Biomatik Category Protein Prices $3,860.00 Sizes 1 mg Source in vitro E.coli expression system Species Human

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