CNGA4

Gene Symbol CNGA4
Entrez Gene 1262
Alt Symbol CNCA2, CNG-4, CNG4, CNG5, CNGB2, OCNC2, OCNCBETA, OCNCb
Species Human
Gene Type protein-coding
Description cyclic nucleotide gated channel alpha 4
Other Description CNG channel alpha-4|cyclic nucleotide gated channel beta 2|cyclic nucleotide-gated cation channel alpha-4
Swissprots Q8IV77
Accessions CAD42376 CAD42377 EAW68736 Q8IV77 AK122736 AK302551 BAG63820 BC040277 AAH40277 BC106935 BC106936 BC160170 AAI60170 DB238337 XM_006718145 XP_006718208 XM_011519899 XP_011518201 NM_001037329 NP_001032406
Function Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Top Pathways Olfactory transduction, cAMP signaling pathway

CNG-4 CRISPR/Cas9 KO Plasmid (h) - sc-410734 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CNG-4 HDR Plasmid (h) - sc-410734-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CNG-4 Double Nickase Plasmid (h) - sc-410734-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CNG-4 Double Nickase Plasmid (h2) - sc-410734-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CNG-4 CRISPR Activation Plasmid (h) - sc-410734-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CNG-4 CRISPR Activation Plasmid (h2) - sc-410734-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CNG-4 Lentiviral Activation Particles (h) - sc-410734-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CNG-4 Lentiviral Activation Particles (h2) - sc-410734-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CNG-4 siRNA (h) - sc-96827 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CNG-4 shRNA Plasmid (h) - sc-96827-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CNG-4 shRNA (h) Lentiviral Particles - sc-96827-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU151011 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6302 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6302 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CNGA4 siRNA (Human) - CRH0882 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CNGA4 - MBS827924 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CNGA4 (NM_001037329.3) - SHH266189 from Creative biogene

Category siRNA
Species Reactivities Human

CNGA4 shRNA Plasmid (Human) - CHH0882 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CNGA4 miRNA 3'UTR clone - MiUTR4H-TG02215 from Creative biogene

Species Reactivities Human
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