PYDC1

Gene Symbol PYDC1
Entrez Gene 260434
Alt Symbol ASC2, POP1, PYC1
Species Human
Gene Type protein-coding
Description PYD (pyrin domain) containing 1
Other Description PAAD-only protein 1|pyrin domain-containing protein 1|pyrin-only protein 1
Swissprots B2R8L4 Q8WXC3 Q8NFP8
Accessions EAW52147 Q8WXC3 AF086332 AF454669 AAL58439 AF467809 AAN03745 AK313418 BAG36211 AY163727 AAO23114 BC105033 AAI05034 BC105035 AAI05036 NM_152901 NP_690865
Function Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS. {ECO:0000269|PubMed:12656673}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12656673}.
Tissue Specificity Predominantly expressed in monocytes, macrophages and granulocytes. {ECO:0000269|PubMed:12656673}.
Top Pathways NOD-like receptor signaling pathway

PYDC1 Antibody Blocking Peptide - LS-E2202 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PYDC1-Antibody-Center-Blocking-Peptide - BP13124c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Pyrin domain-containing protein 1(PYDC1) - CSB-YP848836HU CSB-EP848836HU CSB-BP848836HU CSB-MP848836HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

PYDC1 - TP311240 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
PYDC1

PYDC1 Peptide, Human - M34GP12778H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

POP1 Recombinant Protein - 90-303 from ProSci

Category Protein
Prices $275.00
Sizes 10 µg
Source E. coli
Species Human

Pyrin domain-containing protein 1 (PYDC1), Recombinant Protein - MBS1399699 from MyBioSource

Category Protein
Prices $820.00, $820.00, $1,045.00, $1,045.00, $1,165.00, $1,165.00, $1,625.00, $1,625.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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