PYDC1

Gene Symbol PYDC1
Entrez Gene 260434
Alt Symbol ASC2, POP1, PYC1
Species Human
Gene Type protein-coding
Description PYD (pyrin domain) containing 1
Other Description PAAD-only protein 1|pyrin domain-containing protein 1|pyrin-only protein 1
Swissprots B2R8L4 Q8WXC3 Q8NFP8
Accessions EAW52147 Q8WXC3 AF086332 AF454669 AAL58439 AF467809 AAN03745 AK313418 BAG36211 AY163727 AAO23114 BC105033 AAI05034 BC105035 AAI05036 NM_152901 NP_690865
Function Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS. {ECO:0000269|PubMed:12656673}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12656673}.
Tissue Specificity Predominantly expressed in monocytes, macrophages and granulocytes. {ECO:0000269|PubMed:12656673}.
Top Pathways NOD-like receptor signaling pathway

ASC2 CRISPR/Cas9 KO Plasmid (h) - sc-409521 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASC2 HDR Plasmid (h) - sc-409521-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASC2 Double Nickase Plasmid (h) - sc-409521-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASC2 Double Nickase Plasmid (h2) - sc-409521-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASC2 CRISPR Activation Plasmid (h) - sc-409521-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASC2 CRISPR Activation Plasmid (h2) - sc-409521-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASC2 Lentiviral Activation Particles (h) - sc-409521-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASC2 Lentiviral Activation Particles (h2) - sc-409521-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ASC2 siRNA (h) - sc-93399 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASC2 shRNA Plasmid (h) - sc-93399-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASC2 shRNA (h) Lentiviral Particles - sc-93399-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU139511 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17770 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17770 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00953 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00953

PYDC1 siRNA (Human) - CRJ6824 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PYDC1 (NM_152901.2) - SHH387412 from Creative biogene

Category siRNA
Species Reactivities Human

PYDC1 shRNA Plasmid (Human) - CHJ6824 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PYDC1 miRNA 3'UTR clone - MiUTR1H-08523 from Creative biogene

Species Reactivities Human
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