MAP3K2

Gene Symbol MAP3K2
Entrez Gene 10746
Alt Symbol MEKK2, MEKK2B
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase kinase kinase 2
Other Description MAP/ERK kinase kinase 2|MAPK/ERK kinase kinase 2|MEK kinase 2|MEKK 2
Swissprots Q53QL9 Q59GZ6 Q53S75 Q9NYK3 Q8NC32 Q9Y2U5 B9EG87
Accessions AAY15043 AAY15070 CAJ15104 EAW95315 EAW95316 Q9Y2U5 AB208963 BAD92200 AF111105 AAD28547 AF239798 AAF63496 AI760702 AK027345 BAB55050 AK074577 AK075004 BAC11348 AK093893 AK315007 BC065755 AAH65755 BC136293 AAI36294 BM470563 BQ423724 W07290 NM_006609 NP_006600
Function Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics. {ECO:0000250, ECO:0000269|PubMed:10713157, ECO:0000269|PubMed:16001074}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15075238}. Nucleus {ECO:0000269|PubMed:15075238}. Note=Upon EGF stimulation, translocates into the nucleus.
Top Pathways Gap junction, GnRH signaling pathway, MAPK signaling pathway

Human MAP3K2 ORF Clone(NM_006609.4) - CDCL169549 from Creative Biomart

Species Human
Accession NM_006609.4

Human MAP3K2 ORF clone (NM_006609.3) - CDCB157496 from Creative biogene

Species Human
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