MAP3K2

Gene Symbol	MAP3K2
Entrez Gene	10746
Alt Symbol	MEKK2, MEKK2B
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase kinase kinase 2
Other Description	MAP/ERK kinase kinase 2|MAPK/ERK kinase kinase 2|MEK kinase 2|MEKK 2
Swissprots	Q53QL9 Q59GZ6 Q53S75 Q9NYK3 Q8NC32 Q9Y2U5 B9EG87
Accessions	AAY15043 AAY15070 CAJ15104 EAW95315 EAW95316 Q9Y2U5 AB208963 BAD92200 AF111105 AAD28547 AF239798 AAF63496 AI760702 AK027345 BAB55050 AK074577 AK075004 BAC11348 AK093893 AK315007 BC065755 AAH65755 BC136293 AAI36294 BM470563 BQ423724 W07290 NM_006609 NP_006600
Function	Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics. {ECO:0000250, ECO:0000269|PubMed:10713157, ECO:0000269|PubMed:16001074}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15075238}. Nucleus {ECO:0000269|PubMed:15075238}. Note=Upon EGF stimulation, translocates into the nucleus.
Top Pathways	Gap junction, GnRH signaling pathway, MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human MEKK2 full length protein - ab135009 from Abcam Category Protein Prices $465.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human MEKK2 full length protein - ab85299 from Abcam Category Protein Prices $302.00, $352.00, $1,845.00 Sizes 5 µg, 10 µg, 100 µg Source Baculovirus infected sf9 cells Species Human

Human MEKK2 protein fragment - ab161135 from Abcam Category Protein Source Wheat germ Species Human

MAP3K2 / MEKK2 Antibody Blocking Peptide - LS-E2808 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAP3K2 / MEKK2 Antibody Blocking Peptide - LS-E17795 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MEKK2 Partial Recombinant Protein - H00010746-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MAP3K2 Blocking Peptide - 33R-1147 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MEKK2 Blocking Peptide - abx064235 from Abbexa Category Peptide Species Human, Mouse, Rat

MAP3K2 - H00010746-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MAP3K2 - H00010746-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MAP3K2 - P5589 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

MEKK2, Active Human Recombinant Protein - GWB-PS4378 from Genway Biotech Category Protein Prices $537.00 Sizes 10 µg Species Human

Recombinant Human MAP3K2, GST-tagged, Active - MAP3K2-351H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus.

Recombinant Human MAP3K2 - MAP3K2-30191TH from Creative Biomart Category Protein

Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 2, GST-tagged - MAP3K2-1258H from Creative Biomart Category Protein Source Insect cells Species Human

MEKK2 Blocking Peptide - CBP3041 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Human Mitogen-activated protein kinase kinase kinase 2(MAP3K2) - CSB-YP013424HU CSB-EP013424HU CSB-BP013424HU CSB-MP013424HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MAP3K2 - TP323988 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Species Human

Recombinant Human MEKK2 GST-tagged - CSI13420 from Cell Science Prices $615.00 Sizes 10 μg Species Human

Recombinant Human MEKK2 GST - CRS164A from Cell Science Prices $350.00 Sizes 5 μg Species Human

Recombinant Human MEKK2 GST - CRS164B from Cell Science Prices $495.00 Sizes 10 μg Species Human

MEKK2 Recombinant Protein Antigen - NBP2-48554PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MEKK2-Antibody-N-term-Blocking-Peptide - BP7908a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAP3K2 Peptide, Human - M34GP09172H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mitogen-activated protein kinase kinase kinase 2 (MAP3K2), Recombinant Protein - MBS1416773 from MyBioSource Category Protein Prices $1,415.00, $1,415.00, $1,640.00, $1,640.00, $2,390.00, $2,390.00, $2,830.00, $2,830.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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