CCL4

Gene Symbol CCL4
Entrez Gene 6351
Alt Symbol ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4
Species Human
Gene Type protein-coding
Description chemokine (C-C motif) ligand 4
Other Description C-C motif chemokine 4|G-26 T-lymphocyte-secreted protein|MIP-1-beta(1-69)|PAT 744|SIS-gamma|T-cell activation protein 2|lymphocyte activation gene 1 protein|macrophage inflammatory protein 1-beta|secreted protein G-26|small inducible cytokine A4 (homologous to mouse Mip-1b)
Swissprots Q3SXL8 Q13704 P13236 Q6FGI8 P22617
Accessions AAX07292 AAX07293 EAW80098 P13236 AA362169 AY312578 AAR16183 AY766446 AAX07305 AY766448 AAX07307 BC027961 BC104226 AAI04227 BC104227 AAI04228 BC107433 AAI07434 CR542119 CAG46916 J04130 AAA51576 M23502 AAA36656 M25316 AAA57256 M57503 AAA36752 X16166 CAA34291 X53683 CAA37723 NM_002984 NP_002975
Function Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. {ECO:0000269|PubMed:10540332, ECO:0000269|PubMed:12070155, ECO:0000269|PubMed:8525373}.
Subcellular Location Secreted.
Top Pathways Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, Cytosolic DNA-sensing pathway, Chemokine signaling pathway, Salmonella infection

Human-CCL4-cDNA-Clone - DC09349 from Abgent, a WuXi AppTec company

Prices $125.55
Sizes 10 µg
Species Human
Accession BC104226

CCL4 - MBS1266485 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC104226

Human CCL4 ORF clone(NM_002984.2) - CDCL183115 from Creative biogene

Species Human

Human CCL4L1 ORF clone(NM_001001435.2) - CDCL183118 from Creative biogene

Species Human

Human CCL4L2 ORF Clone(NM_207007.2) - CDCR327821 from Creative biogene

Species Human

Human CCL4 ORF Clone (BC104226) - CDCS411079 from Creative biogene

Species Human
Accession P13236

Human CCL4L1 cDNA Clone(NM_001001435.2) - CDFH002950 from Creative biogene

Species Human

Human CCL4L2 cDNA Clone(NM_207007.2) - CDFG013719 from Creative biogene

Species Human

Human CCL4L2 cDNA Clone(NM_207007.2) - CDFG013722 from Creative biogene

Species Human
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